Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SLC22A4 | Q9H015 | 1/20 | 0.51 |
| ▸ | SLC7A5 | Q01650 | 4/20 | 0.50 |
| ▸ | CYP3A4 | P08684 | 3/20 | 0.50 |
| ▸ | KDM4E | B2RXH2 | 4/20 | 0.42 |
| ▸ | LMNA | P02545 | 3/20 | 0.42 |
| ▸ | MAPT | P10636 | 3/20 | 0.42 |
| ▸ | BLM | P54132 | 3/20 | 0.42 |
| ▸ | PMP22 | Q01453 | 3/20 | 0.42 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.42 |
| ▸ | HIF1A | Q16665 | 3/20 | 0.42 |
| ▸ | TSHR | P16473 | 2/20 | 0.42 |
| ▸ | MEN1 | O00255 | 2/20 | 0.42 |
| ▸ | MPO | P05164 | 1/20 | 0.42 |
| ▸ | PKM | P14618 | 2/20 | 0.42 |
| ▸ | PTGS1 | P23219 | 2/20 | 0.42 |
| ▸ | ALPI | P09923 | 1/20 | 0.42 |
| ▸ | XIAP | P98170 | 1/20 | 0.42 |
| ▸ | KDM3B | Q7LBC6 | 1/20 | 0.40 |
| ▸ | HSD17B10 | Q99714 | 4/20 | 0.39 |
| ▸ | ALOX15 | P16050 | 3/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL12800006 | 1.00 | SLC22A4 (0.51) | SLC22A4SLC7A5CYP3A4KDM4ELMNA | |
| SCHEMBL1867165 | 1.00 | SLC22A4 (0.51) | SLC22A4SLC7A5CYP3A4KDM4ELMNA | |
| SCHEMBL26659419 | 0.81 | SLC7A5 (0.51) | SLC7A5CYP3A4KDM4ELMNAMAPT | |
| SCHEMBL9604220 | 0.79 | SLC22A4 (0.55) | SLC22A4KDM4ELMNAMAPTKMT2A | |
| SCHEMBL27788682 | 0.79 | KMT2A (0.49) | SLC7A5CYP3A4KDM4ELMNAMAPT | |
| SCHEMBL5294228 | 0.77 | SMN1; SMN2 (0.47) | SLC7A5CYP3A4KDM4ELMNAMAPT | |
| SCHEMBL12039657 | 0.76 | SLC22A4 (0.76) | SLC22A4KMT2AKDM3BTDP1POLB | |
| SCHEMBL9604977 | 0.76 | SLC22A4 (0.51) | SLC22A4CYP3A4KDM4EKMT2AKDM3B | |
| SCHEMBL15127703 | 0.76 | SLC22A4 (0.51) | SLC22A4MAPTKMT2AKDM3BALDH1A1 | |
| SCHEMBL12800017 | 0.76 | SLC22A4 (0.51) | SLC22A4MAPTKMT2AKDM3BALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 25 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7767826-B2 | Process for the synthesis of L-(+)-ergothioneine | PHARMATECH INTERNATIONAL, INC. (US) | 2010-08-03 | — | — | US | claimed |
| US-20090093642-A1 | PROCESS FOR THE SYNTHESIS OF L-(+)-ERGOTHIONEINE | PHARMATECH INTERNATIONAL, INC. | 2009-04-09 | — | — | US | claimed |
| WO-2009045413-A1 | PROCESS FOR THE SYNTHESIS OF L-(+)-ERGOTHIONEINE | PHARMATECH INTERNATIONAL, INC. (US) | 2009-04-09 | — | — | WO | claimed |
| WO-2023220754-A1 | ANTIOXIDANT DERIVATIVE OF HYALURONIC ACID | UNIVERSITY OF VERMONT AND STATE AGRICULTURAL COLLEGE (US) | 2023-11-16 | — | — | WO | disclosed |
| EP-2486019-B1 | METHOD FOR THE SYNTHESIS OF 2-THIOHISTIDINE AND THE LIKE | TETRAHEDRON (FR) | 2015-03-25 | — | — | EP | disclosed |
| US-8835477-B2 | Method for the synthesis of 2-thiohistidine and the like | TETRAHEDRON (FR) | 2014-09-16 | — | — | US | disclosed |
| US-8835477-B2 | Method for the synthesis of 2-thiohistidine and the like | TETRAHEDRON (FR) | 2014-09-16 | — | — | US | disclosed |
| EP-1938793-B1 | Use in cosmetics of L-2-thiohistidine or one of its derivatives as a depigmentation agent | LVMH RECH (FR) | 2013-10-02 | — | — | EP | disclosed |
| US-20130123465-A1 | MONOMETHYLVALINE COMPOUNDS HAVING PHENYLALANINE SIDE-CHAIN MODIFICATIONS AT THE C-TERMINUS | SEATTLE GENETICS, INC. (US) | 2013-05-16 | — | — | US | disclosed |
| CN-101209229-B | Use in cosmetics of L-2-thiohistidine or one of its derivatives as a depigmentation agent | LVMH RECH | 2013-03-20 | — | — | CN | disclosed |
| US-8343928-B2 | Monomethylvaline compounds having phenylalanine side-chain replacements at the C-terminus | SEATTLE GENETICS, INC. (US) | 2013-01-01 | — | — | US | disclosed |
| US-7767826-B2 | Process for the synthesis of L-(+)-ergothioneine | PHARMATECH INTERNATIONAL, INC. (US) | 2010-08-03 | — | — | US | disclosed |
| US-20090093642-A1 | PROCESS FOR THE SYNTHESIS OF L-(+)-ERGOTHIONEINE | PHARMATECH INTERNATIONAL, INC. | 2009-04-09 | — | — | US | disclosed |
| US-20090093642-A1 | PROCESS FOR THE SYNTHESIS OF L-(+)-ERGOTHIONEINE | PHARMATECH INTERNATIONAL, INC. | 2009-04-09 | — | — | US | disclosed |
| WO-2009045413-A1 | PROCESS FOR THE SYNTHESIS OF L-(+)-ERGOTHIONEINE | PHARMATECH INTERNATIONAL, INC. (US) | 2009-04-09 | — | — | WO | disclosed |
| US-20090018086-A1 | Monomethylvaline Compounds Having Phenylalanine Side-Chain Replacements at the C-Terminus | SEATTLE GENETICS, INC. (US) | 2009-01-15 | — | — | US | disclosed |
| US-20090018086-A1 | Monomethylvaline Compounds Having Phenylalanine Side-Chain Replacements at the C-Terminus | SEATTLE GENETICS, INC. (US) | 2009-01-15 | — | — | US | disclosed |
| US-20080161377-A1 | Use of L-2-thiohistidine or one of its derivatives as a depigmenting agent in cosmetics | LVMH RECHERCHE (FR) | 2008-07-03 | — | — | US | disclosed |
| EP-1938793-A2 | Use in cosmetics of L-2-thiohistidine or one of its derivatives as a depigmentation agent | LVMH RECHERCHE (FR) | 2008-07-02 | — | — | EP | disclosed |
| CN-101209229-A | Use in cosmetics of L-2-thiohistidine or one of its derivatives as a depigmentation agent | LVMH RECH (FR) | 2008-07-02 | — | — | CN | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (3 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20130123465-A1 | MONOMETHYLVALINE COMPOUNDS HAVING PHENYLALANINE SIDE-CHAIN MODIFICATIONS AT THE C-TERMINUS | MMAB, PTMS, DNPEP | SLC22A4 3831/4885SLC7A5 50/4885CYP3A4 2439/4885 |
| US-20090018086-A1 | Monomethylvaline Compounds Having Phenylalanine Side-Chain Replacements at the C-Terminus | MMAB, DNPEP, MARCKS | SLC22A4 3694/4885SLC7A5 39/4885CYP3A4 2540/4885 |
| US-20090093642-A1 | PROCESS FOR THE SYNTHESIS OF L-(+)-ERGOTHIONEINE | TTPA, DTYMK, TST | SLC22A4 2504/4885SLC7A5 205/4885CYP3A4 1118/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.