Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SLC22A4 | Q9H015 | 1/20 | 0.51 |
| ▸ | KDM3B | Q7LBC6 | 1/20 | 0.37 |
| ▸ | ITGB2 | P05107 | 2/20 | 0.33 |
| ▸ | ICAM1 | P05362 | 2/20 | 0.33 |
| ▸ | ITGAL | P20701 | 2/20 | 0.33 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.33 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.33 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.32 |
| ▸ | GAA | P10253 | 1/20 | 0.32 |
| ▸ | GFER | P55789 | 1/20 | 0.32 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.31 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.31 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.31 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.31 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.31 |
| ▸ | ACE | P12821 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL26882134 | 0.85 | SLC22A4 (0.49) | SLC22A4KDM3BITGB2ICAM1ITGAL | |
| SCHEMBL26882364 | 0.81 | SLC22A4 (0.46) | SLC22A4KMT2ATDP1KDM4EGAA | |
| SCHEMBL9604220 | 0.79 | SLC22A4 (0.55) | SLC22A4KDM3BKMT2ATDP1KDM4E | |
| SCHEMBL12800006 | 0.76 | SLC22A4 (0.51) | SLC22A4KDM3BKMT2ATDP1KDM4E | |
| SCHEMBL1867165 | 0.76 | SLC22A4 (0.51) | SLC22A4KDM3BKMT2ATDP1KDM4E | |
| SCHEMBL175156 | 0.75 | SLC22A4 (0.76) | SLC22A4KDM3BKMT2ATDP1GAA | |
| SCHEMBL745229 | 0.75 | SLC22A4 (0.76) | SLC22A4KDM3BKMT2ATDP1GAA | |
| SCHEMBL26882423 | 0.74 | SLC22A4 (0.47) | SLC22A4KDM3BKMT2ATDP1KDM4E | |
| SCHEMBL151336 | 0.70 | ITGB2 (0.60) | ITGB2ICAM1ITGALKMT2AKDM4E | |
| SCHEMBL163397 | 0.70 | ITGB2 (0.60) | ITGB2ICAM1ITGALKMT2AKDM4E |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 11 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2023220754-A1 | ANTIOXIDANT DERIVATIVE OF HYALURONIC ACID | UNIVERSITY OF VERMONT AND STATE AGRICULTURAL COLLEGE (US) | 2023-11-16 | — | — | WO | disclosed |
| EP-2486020-B1 | METHOD FOR THE SYNTHESIS OF ERGOTHIONEINE AND THE LIKE | TETRAHEDRON (FR) | 2017-08-16 | — | — | EP | disclosed |
| EP-2486019-B1 | METHOD FOR THE SYNTHESIS OF 2-THIOHISTIDINE AND THE LIKE | TETRAHEDRON (FR) | 2015-03-25 | — | — | EP | disclosed |
| US-8835477-B2 | Method for the synthesis of 2-thiohistidine and the like | TETRAHEDRON (FR) | 2014-09-16 | — | — | US | disclosed |
| US-8835477-B2 | Method for the synthesis of 2-thiohistidine and the like | TETRAHEDRON (FR) | 2014-09-16 | — | — | US | disclosed |
| US-8399500-B2 | Method of synthesizing ergothioneine and analogs | TETRAHEDRON (FR) | 2013-03-19 | — | — | US | disclosed |
| US-20120330029-A1 | METHOD FOR THE SYNTHESIS OF 2-THIOHISTIDINE AND THE LIKE | TETRAHEDRON (FR) | 2012-12-27 | — | — | US | disclosed |
| US-20120330029-A1 | METHOD FOR THE SYNTHESIS OF 2-THIOHISTIDINE AND THE LIKE | TETRAHEDRON (FR) | 2012-12-27 | — | — | US | disclosed |
| US-20120136159-A1 | THE METHOD OF SYNTHESIZING ERGOTHIONEINE AND ANALOGS | TERTRAHEDRON (FR) | 2012-05-31 | — | — | US | disclosed |
| WO-2011042480-A1 | METHOD FOR THE SYNTHESIS OF ERGOTHIONEINE AND THE LIKE | TETRAHEDRON (FR) | 2011-04-14 | — | — | WO | disclosed |
| WO-2011042478-A1 | METHOD FOR THE SYNTHESIS OF 2-THIOHISTIDINE AND THE LIKE | TETRAHEDRON (FR) | 2011-04-14 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20120136159-A1 | THE METHOD OF SYNTHESIZING ERGOTHIONEINE AND ANALOGS | TST, SLC6A12, TTPA | SLC22A4 331/4885KDM3B 4522/4885ITGB2 4352/4885 |
| US-20120330029-A1 | METHOD FOR THE SYNTHESIS OF 2-THIOHISTIDINE AND THE LIKE | TST, CTH, TPMT | SLC22A4 1293/4885KDM3B 3157/4885ITGB2 3730/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.