Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SLC22A4 | Q9H015 | 1/20 | 0.55 |
| ▸ | APAF1 | O14727 | 3/20 | 0.42 |
| ▸ | POLB | P06746 | 2/20 | 0.42 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.42 |
| ▸ | MAPT | P10636 | 1/20 | 0.42 |
| ▸ | RECQL | P46063 | 1/20 | 0.42 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.42 |
| ▸ | KDM3B | Q7LBC6 | 1/20 | 0.40 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.35 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.35 |
| ▸ | LMNA | P02545 | 1/20 | 0.32 |
| ▸ | TBXAS1 | P24557 | 2/20 | 0.31 |
| ▸ | MME | P08473 | 3/20 | 0.31 |
| ▸ | ACE | P12821 | 3/20 | 0.31 |
| ▸ | GAA | P10253 | 1/20 | 0.31 |
| ▸ | GFER | P55789 | 1/20 | 0.31 |
| ▸ | GABRR1 | P24046 | 2/20 | 0.31 |
| ▸ | RXRA | P19793 | 1/20 | 0.31 |
| ▸ | NR4A2 | P43354 | 1/20 | 0.31 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL25661031 | 0.68 | APAF1 (0.47) | APAF1POLBKDM4EMAPTRECQL | |
| SCHEMBL15012539 | 0.67 | APAF1 (0.54) | APAF1POLBKDM4EMAPTRECQL | |
| SCHEMBL791747 | 0.67 | CYP3A4 (0.65) | KDM4EMAPTKMT2ALMNATBXAS1 | |
| SCHEMBL14411160 | 0.67 | CYP3A4 (0.65) | KDM4EMAPTKMT2ALMNATBXAS1 | |
| SCHEMBL29062772 | 0.67 | APAF1 (0.40) | APAF1POLBKDM4EMAPTRECQL | |
| SCHEMBL5159413 | 0.62 | ADAMTS4 (0.54) | APAF1POLBKDM4EMAPTRECQL | |
| SCHEMBL11237591 | 0.62 | TBXAS1 (0.59) | LMNATBXAS1MMEACECYP1A2 | |
| SCHEMBL18072719 | 0.61 | APAF1 (0.41) | APAF1POLBKDM4EMAPTRECQL | |
| SCHEMBL25661026 | 0.61 | CAPN1 (0.44) | APAF1POLBKDM4EMAPTRECQL | |
| SCHEMBL3670921 | 0.60 | APAF1 (0.40) | APAF1POLBKDM4EMAPTRECQL |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20170305865-A1 | PROCESS FOR SYNTHESIZING ERGOTHIONEINE AND RELATED COMPOUNDS | UNIVERSITY OF CAPE TOWN (ZA) | 2017-10-26 | — | — | US | disclosed |
| US-8399500-B2 | Method of synthesizing ergothioneine and analogs | TETRAHEDRON (FR) | 2013-03-19 | — | — | US | disclosed |
| US-20120136159-A1 | THE METHOD OF SYNTHESIZING ERGOTHIONEINE AND ANALOGS | TERTRAHEDRON (FR) | 2012-05-31 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20120136159-A1 | THE METHOD OF SYNTHESIZING ERGOTHIONEINE AND ANALOGS | TST, SLC6A12, TTPA | SLC22A4 331/4885APAF1 4409/4885POLB 1406/4885 |
| US-20170305865-A1 | PROCESS FOR SYNTHESIZING ERGOTHIONEINE AND RELATED COMPOUNDS | CTH, FTH1, TXN | SLC22A4 1267/4885APAF1 4385/4885POLB 2904/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.