SCHEMBL18674301

SCHEMBL18674301

C#Cc1ccc(-n2c3ccc(C)cc3c3cc(C)ccc32)cc1

nearest known ligand 0.36

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
POLB P06746 3/20 0.36
MAPT P10636 2/20 0.35
KDM4E B2RXH2 1/20 0.35
GAA P10253 1/20 0.35
USP14 P54578 3/20 0.34
MPO P05164 1/20 0.33
NPC1 O15118 1/20 0.33
RAB9A P51151 1/20 0.33
KMT2A Q03164 1/20 0.33
CYP19A1 P11511 1/20 0.32
GABRA1 P14867 1/20 0.32
GABRG2 P18507 1/20 0.32
GABRB3 P28472 1/20 0.32
GABRA5 P31644 1/20 0.32
GABRA2 P47869 1/20 0.32
GABRA6 Q16445 1/20 0.32
BCHE P06276 1/20 0.31
ACHE P22303 1/20 0.31
PARP15 Q460N3 2/20 0.31
PARP14 Q460N5 2/20 0.31

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL28563883 0.85 GABRG2 (0.36) KDM4EUSP14MPOGABRA1GABRG2
SCHEMBL15025823 0.85 POLB (0.44) POLBMAPTKDM4EGAAUSP14
SCHEMBL9913062 0.83 POLB (0.46) POLBMAPTKDM4EGAAUSP14
SCHEMBL12721573 0.83 ALDH1A1 (0.50) POLBMAPTKDM4EGAAUSP14
SCHEMBL13495025 0.82 POLB (0.32) POLBMAPTKDM4EGAAUSP14
SCHEMBL18674306 0.81 POLB (0.35) POLBMAPTKDM4EGAAUSP14
SCHEMBL4377057 0.80 GABRA1 (0.38) MPOGABRA1GABRG2GABRB3GABRA5
SCHEMBL29447739 0.80 POLB (0.41) POLBMAPTKDM4EGAAUSP14
SCHEMBL12544709 0.80 POLB (0.41) POLBMAPTKDM4EGAAUSP14
SCHEMBL13231732 0.80 POLB (0.44) POLBMAPTKDM4EGAAUSP14

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20170092876-A1 PHOTOELECTRIC CONVERSION ELEMENT, SOLID-STATE IMAGING DEVICE, ORGANIC LIGHT-ABSORBING MATERIAL, AND ORGANIC LIGHT-ABSORBING MATERIAL INTERMEDIATE SONY CORPORATION (JP) 2017-03-30 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20170092876-A1 PHOTOELECTRIC CONVERSION ELEMENT, SOLID-STATE IMAGING DEVICE, ORGANIC LIGHT-ABSORBING MATERIAL, AND ORGANIC LIGHT-ABSORBING MATERIAL INTERMEDIATE L1CAM, ASIC1, EPN1 POLB 1282/4885MAPT 1010/4885KDM4E 3821/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.