Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ACVR1 | Q04771 | 3/20 | 0.45 |
| ▸ | PDGFRA | P16234 | 2/20 | 0.45 |
| ▸ | LTK | P29376 | 2/20 | 0.45 |
| ▸ | DYRK1B | Q9Y463 | 2/20 | 0.45 |
| ▸ | LRRK2 | Q5S007 | 2/20 | 0.45 |
| ▸ | FER | P16591 | 1/20 | 0.45 |
| ▸ | CDK8 | P49336 | 1/20 | 0.45 |
| ▸ | CA12 | O43570 | 2/20 | 0.41 |
| ▸ | CA1 | P00915 | 2/20 | 0.41 |
| ▸ | CA2 | P00918 | 2/20 | 0.41 |
| ▸ | CA4 | P22748 | 2/20 | 0.41 |
| ▸ | CA7 | P43166 | 2/20 | 0.41 |
| ▸ | CA9 | Q16790 | 2/20 | 0.41 |
| ▸ | PDE7A | Q13946 | 1/20 | 0.41 |
| ▸ | PDE7B | Q9NP56 | 1/20 | 0.41 |
| ▸ | MAOA | P21397 | 1/20 | 0.41 |
| ▸ | MAOB | P27338 | 1/20 | 0.41 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.41 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.41 |
| ▸ | PLCG1 | P19174 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL15672895 | 0.87 | KMT2A (0.41) | CA12CA1CA2CA4CA7 | |
| SCHEMBL5697347 | 0.78 | ACVR1 (0.67) | ACVR1PDGFRALTKDYRK1BLRRK2 | |
| SCHEMBL8590983 | 0.67 | ACVR1 (0.44) | ACVR1PDGFRALTKDYRK1BLRRK2 | |
| SCHEMBL16477920 | 0.65 | MEN1 (0.34) | CA12CA1CA2CA4CA7 | |
| SCHEMBL31501686 | 0.65 | MEN1 (0.34) | CA12CA1CA2CA4CA7 | |
| SCHEMBL2235632 | 0.65 | PDE7A (0.62) | ACVR1PDGFRALTKDYRK1BLRRK2 | |
| SCHEMBL11168286 | 0.64 | ACVR1 (0.41) | ACVR1PDGFRALTKDYRK1BLRRK2 | |
| SCHEMBL12242976 | 0.64 | ACVR1 (0.56) | ACVR1PDGFRALTKDYRK1BLRRK2 | |
| SCHEMBL3541086 | 0.64 | MEN1 (0.33) | CA12CA1CA2CA4CA7 | |
| SCHEMBL6309542 | 0.64 | PDE7A (0.50) | ACVR1PDGFRALTKDYRK1BLRRK2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 7 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-11772085-B2 | Far superior oxidation catalysts based on macrocyclic compounds | CARNEGIE MELLON UNIVERSITY (US) | 2023-10-03 | — | — | US | disclosed |
| US-11772085-B2 | Far superior oxidation catalysts based on macrocyclic compounds | CARNEGIE MELLON UNIVERSITY (US) | 2023-10-03 | — | — | US | disclosed |
| EP-4015511-A1 | OXIDATION CATALYSTS BASED ON MACROCYCLIC COMPOUNDS | CARNEGIE MELLON UNIVERSITY (US) | 2022-06-22 | — | — | EP | disclosed |
| EP-3353157-B1 | OXIDATION CATALYSTS BASED ON MACROCYCLIC COMPOUNDS | UNIV CARNEGIE MELLON (US) | 2021-11-24 | — | — | EP | disclosed |
| US-20210086171-A1 | FAR SUPERIOR OXIDATION CATALYSTS BASED ON MACROCYCLIC COMPOUNDS | CARNEGIE MELLON UNIVERSITY | 2021-03-25 | — | — | US | disclosed |
| US-10926248-B2 | Far superior oxidation catalysts based on macrocyclic compounds | CARNEGIE MELLON UNIVERSITY (US) | 2021-02-23 | — | — | US | disclosed |
| WO-2017053564-A1 | FAR SUPERIOR OXIDATION CATALYSTS BASED ON MACROCYCLIC COMPOUNDS | CARNEGIE MELLON UNIVERSITY (US) | 2017-03-30 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (3 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-10926248-B2 | Far superior oxidation catalysts based on macrocyclic compounds | ME3, SOD1, DUOX1 | ACVR1 4792/4885PDGFRA 4832/4885LTK 1878/4885 |
| US-11772085-B2 | Far superior oxidation catalysts based on macrocyclic compounds | SOD1, ME3, ME2 | ACVR1 4760/4885PDGFRA 4830/4885LTK 1975/4885 |
| US-20210086171-A1 | FAR SUPERIOR OXIDATION CATALYSTS BASED ON MACROCYCLIC COMPOUNDS | ME3, ME2, ME1 | ACVR1 4718/4885PDGFRA 4731/4885LTK 1898/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.