Known targets — ChEMBL curated mechanism
ACHEBDKRB2CHRM1CHRM2CHRM3CHRNA1CHRNB1CHRNDCHRNECHRNGGUCY1A1GUCY1A2GUCY1B1GUCY1B2NAMPTPTAFRSLC10A2SLC6A2SLC6A3TACR1dacAdacBdacCftsImrcAmrcBmrdA
The experimentally established mechanism targets of Hydrochloric Acid. The predicted profile below is derived independently by chemical similarity — agreement is a validation signal, a miss is honest.
Predicted protein targets (top 6)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | BDKRB2 known ✓ | P30411 | 4/20 | 0.45 |
| ▸ | DNM1 | Q05193 | 6/20 | 0.68 |
| ▸ | TSHR | P16473 | 1/20 | 0.47 |
| ▸ | THRB | P10828 | 1/20 | 0.47 |
| ▸ | LMNA | P02545 | 1/20 | 0.40 |
| ▸ | OPRM1 | P35372 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Hydrochloric Acid SCHEMBL3781268 | 1.00 | DNM1 (0.68) | DNM1TSHRTHRBBDKRB2LMNA | |
| Hydrochloric Acid SCHEMBL5085185 | 1.00 | DNM1 (0.68) | DNM1TSHRTHRBBDKRB2LMNA | |
| Hydrochloric Acid SCHEMBL5087808 | 1.00 | DNM1 (0.68) | DNM1TSHRTHRBBDKRB2LMNA | |
| Hydrochloric Acid SCHEMBL5087731 | 1.00 | DNM1 (0.68) | DNM1TSHRTHRBBDKRB2LMNA | |
| Hydrochloric Acid SCHEMBL5085420 | 1.00 | DNM1 (0.68) | DNM1TSHRTHRBBDKRB2LMNA | |
| Hydrochloric Acid SCHEMBL1864955 | 1.00 | DNM1 (0.68) | DNM1TSHRTHRBBDKRB2LMNA | |
| Hydrochloric Acid SCHEMBL5085071 | 1.00 | DNM1 (0.68) | DNM1TSHRTHRBBDKRB2LMNA | |
| Hydrochloric Acid SCHEMBL11119620 | 1.00 | DNM1 (0.68) | DNM1TSHRTHRBBDKRB2LMNA | |
| Hydrochloric Acid SCHEMBL10616392 | 1.00 | DNM1 (0.68) | DNM1TSHRTHRBBDKRB2LMNA | |
| Hydrochloric Acid SCHEMBL5087650 | 1.00 | DNM1 (0.68) | DNM1TSHRTHRBBDKRB2LMNA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 23 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3040421-B1 | METHOD FOR MEASURING CHOLESTEROL IN HIGH-DENSITY LIPOPROTEIN, AND REAGENT FOR USE IN SAID METHOD | SEKISUI MEDICAL CO LTD (JP) | 2018-03-28 | — | — | EP | disclosed |
| EP-2949650-B1 | Synthetic method for the preparation of 1,2-Benzisothiazolin-3-one | SHOUGUANG SYNTECH FINE CHEMICAL CO LTD (CN) | 2017-10-11 | — | — | EP | disclosed |
| US-20160208311-A1 | METHOD FOR MEASURING CHOLESTEROL IN HIGH-DENSITY LIPOPROTEIN, AND REAGENT FOR USE IN SAID METHOD | SEKISUI MEDICAL CO., LTD. (JP) | 2016-07-21 | — | — | US | disclosed |
| EP-3040421-A1 | METHOD FOR MEASURING CHOLESTEROL IN HIGH-DENSITY LIPOPROTEIN, AND REAGENT FOR USE IN SAID METHOD | Sekisui Medical Co., Ltd. (JP) | 2016-07-06 | — | — | EP | disclosed |
| US-9334248-B2 | Synthetic method for the preparation of 1, 2-benzisothiazolin-3-one | SHOUGUANG SYNTECH FINE CHEMICAL CO., LTD. (CN) | 2016-05-10 | — | — | US | disclosed |
| US-9221740-B2 | Method for producing carbonate compound and method for producing aromatic polycarbonate | ASAHI GLASS COMPANY, LIMITED (JP) | 2015-12-29 | — | — | US | disclosed |
| EP-2949650-A1 | Synthetic method for the preparation of 1,2-Benzisothiazolin-3-one | Shouguang Syntech Fine Chemical Co., Ltd. (CN) | 2015-12-02 | — | — | EP | disclosed |
| US-20150336910-A1 | SYNTHETIC METHOD FOR THE PREPARATION OF 1, 2-BENZISOTHIAZOLIN-3-ONE | SYNTECH EURO LIMITED (GB) | 2015-11-26 | — | — | US | disclosed |
| EP-2883861-A1 | METHOD FOR PRODUCING CARBONATE COMPOUND AND METHOD FOR PRODUCING AROMATIC POLYCARBONATE | Asahi Glass Company, Limited (JP) | 2015-06-17 | — | — | EP | disclosed |
| US-20150152037-A1 | METHOD FOR PRODUCING CARBONATE COMPOUND AND METHOD FOR PRODUCING AROMATIC POLYCARBONATE | AGC Inc. (JP) | 2015-06-04 | — | — | US | disclosed |
| WO-2011053470-A2 | SELECTIVE SILICON ETCH PROCESS | SACHEM, INC. (US) | 2011-05-05 | — | — | WO | disclosed |
| US-20110104875-A1 | SELECTIVE SILICON ETCH PROCESS | PNC BANK, NATIONAL ASSOCIATION | 2011-05-05 | — | — | US | disclosed |
| US-20080214386-A1 | Stability; easily separated from solution; surface treatment of catalyst with Group seven compound; reacting epoxide with carbon dioxide | NATIONAL INSTITUTE OF ADVANCED INDUSTRIAL SCIENCE AND TECHNOLOGY (JP) | 2008-09-04 | — | — | US | disclosed |
| EP-0332729-A1 | Vulcanizable chlorinated polyethylene compositions | E.I. DU PONT DE NEMOURS AND COMPANY (US) | 1989-09-20 | — | — | EP | disclosed |
| US-4749521-A | REACTING 1,4-DIAMINO-2,3-DIHALOGENOANTHRAQUINONE WITH SULFONATING AGENT IN PRESCENCE OF QUATERNARY AMMONIUM OR PHOSPHONIUM COMPOUND | SUMITOMO CHEMICAL COMPANY, LTD. (JP) | 1988-06-07 | — | — | US | disclosed |
| US-4745147-A | SULFUR COMPOUND CURING AGENT | E. I. DU PONT DE NEMOURS AND COMPANY (US) | 1988-05-17 | — | — | US | disclosed |
| EP-0105762-B1 | PROCESS FOR PRODUCING ANTHRAQUINONE COMPOUNDS | SUMITOMO CHEMICAL COMPANY, LIMITED (JP) | 1988-03-09 | — | — | EP | disclosed |
| US-4710320-A | REACTING 1-AMINO-2-HALOGENO-4-HYDROXYANTHRAQUINONES WITH PHENOLS IN A SULFOLANE SOLVENT WITH AN ACID BINDING AGENT | SUMITOMO CHEMICAL COMPANY, LIMITED (JP) | 1987-12-01 | — | — | US | disclosed |
| US-4519947-A | SULFONATING 1,4-DIAMINO-2,3-DIHALOGENO-ANTHRAQUINONE | SUMITOMO CHEMICAL CO., LTD. (JP) | 1985-05-28 | — | — | US | disclosed |
| EP-0105762-A2 | Process for producing anthraquinone compounds | SUMITOMO CHEMICAL COMPANY, LIMITED (JP) | 1984-04-18 | — | — | EP | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20150152037-A1 | METHOD FOR PRODUCING CARBONATE COMPOUND AND METHOD FOR PRODUCING AROMATIC POLYCARBONATE | PKD1, CA2, CA11 | BDKRB2 1479/4885DNM1 906/4885TSHR 3475/4885 |
| US-20150336910-A1 | SYNTHETIC METHOD FOR THE PREPARATION OF 1, 2-BENZISOTHIAZOLIN-3-ONE | TST, AQP1, BZW1 | BDKRB2 1940/4885DNM1 3268/4885TSHR 256/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.