Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.44 |
| ▸ | MEN1 | O00255 | 1/20 | 0.44 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.44 |
| ▸ | MAPT | P10636 | 1/20 | 0.44 |
| ▸ | THRB | P10828 | 1/20 | 0.44 |
| ▸ | HPGD | P15428 | 1/20 | 0.44 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.44 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.44 |
| ▸ | ADORA2A | P29274 | 1/20 | 0.43 |
| ▸ | ADORA1 | P30542 | 1/20 | 0.43 |
| ▸ | PNP | P00491 | 2/20 | 0.42 |
| ▸ | NUDT1 | P36639 | 4/20 | 0.40 |
| ▸ | PI4KA | P42356 | 7/20 | 0.38 |
| ▸ | PI4K2B | Q8TCG2 | 7/20 | 0.38 |
| ▸ | PI4K2A | Q9BTU6 | 7/20 | 0.38 |
| ▸ | PI4KB | Q9UBF8 | 7/20 | 0.38 |
| ▸ | LMNA | P02545 | 2/20 | 0.34 |
| ▸ | DRD3 | P35462 | 1/20 | 0.34 |
| ▸ | XDH | P47989 | 1/20 | 0.34 |
| ▸ | LRRK2 | Q5S007 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1868817 | 0.80 | ADORA2A (0.43) | KDM4EMEN1ALDH1A1MAPTTHRB | |
| SCHEMBL3799507 | 0.79 | ADORA2A (0.37) | ADORA2AADORA1NUDT1PI4KAPI4K2B | |
| SCHEMBL42314 | 0.79 | ADORA2A (0.66) | ALDH1A1ADORA2AADORA1NUDT1PI4KA | |
| SCHEMBL29400753 | 0.79 | ADORA2A (0.66) | ALDH1A1ADORA2AADORA1NUDT1PI4KA | |
| SCHEMBL3857164 | 0.78 | AKT2 (0.44) | KDM4EADORA2AADORA1NUDT1PI4KA | |
| Thioguanine SCHEMBL1445605 | 0.77 | PNP (0.48) | ALDH1A1HPGDHSD17B10PNPPI4KA | |
| SCHEMBL320848 | 0.76 | NUDT1 (0.43) | KDM4EMEN1ALDH1A1MAPTTHRB | |
| SCHEMBL6826187 | 0.76 | NUDT1 (0.44) | KDM4EMEN1ALDH1A1MAPTTHRB | |
| SCHEMBL8823867 | 0.76 | ADORA2A (0.35) | ADORA2AADORA1NUDT1PI4KAPI4K2B | |
| SCHEMBL5667619 | 0.76 | ADORA2A (0.43) | KDM4EMEN1ALDH1A1MAPTTHRB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20070160981-A1 | VIRAL PROTEASE | NATIONAL HEALTH RESEARCH INSTITUTES (TW) | 2007-07-12 | — | — | US | disclosed |
| US-6589941-B1 | Preventing or reducing formation of resistance in cytostatic treatment comprising combining BVDU, a salt thereof or BVDU in protected form or in prodrug form with at least one cytostatic agent in order to prevent or reduce the formation | RESPROTECT GMBH (DE) | 2003-07-08 | — | — | US | disclosed |
| EP-0806956-B1 | USE OF 5'SUBSTITUTED NUCLEOSIDES TO PROVIDE RESISTANCE IN CYTOSTATIC TREATMENT | RESPROTECT GMBH (DE) | 2002-08-28 | — | — | EP | disclosed |
| EP-0806956-A1 | USE OF 5'SUBSTITUTED NUCLEOSIDES TO PROVIDE RESISTANCE IN CYTOSTATIC TREATMENT AND MEDICAMENTS CONTAINING SAID NUCLEOSIDES | FRAUNHOFER-GESELLSCHAFT ZUR FÖRDERUNG DER ANGEWANDTEN FORSCHUNG E.V. (DE) | 1997-11-19 | — | — | EP | disclosed |
| WO-1996023506-A1 | USE OF 5'SUBSTITUTED NUCLEOSIDES TO PROVIDE RESISTANCE IN CYTOSTATIC TREATMENT AND MEDICAMENTS CONTAINING SAID NUCLEOSIDES | Fraunhofer-Gesellschaft zur Förderung der angewandten Forschung e.V. (DE) | 1996-08-08 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20070160981-A1 | VIRAL PROTEASE | XPNPEP1, PREP, XPNPEP2 | KDM4E 2733/4885MEN1 4194/4885ALDH1A1 4585/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.