Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NUDT1 | P36639 | 4/20 | 0.44 |
| ▸ | ADORA2A | P29274 | 1/20 | 0.43 |
| ▸ | ADORA1 | P30542 | 1/20 | 0.43 |
| ▸ | PNP | P00491 | 2/20 | 0.42 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.41 |
| ▸ | MEN1 | O00255 | 1/20 | 0.41 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.41 |
| ▸ | MAPT | P10636 | 1/20 | 0.41 |
| ▸ | THRB | P10828 | 1/20 | 0.41 |
| ▸ | HPGD | P15428 | 1/20 | 0.41 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.41 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.41 |
| ▸ | PI4KA | P42356 | 7/20 | 0.38 |
| ▸ | PI4K2B | Q8TCG2 | 7/20 | 0.38 |
| ▸ | PI4K2A | Q9BTU6 | 7/20 | 0.38 |
| ▸ | PI4KB | Q9UBF8 | 7/20 | 0.38 |
| ▸ | LMNA | P02545 | 2/20 | 0.34 |
| ▸ | DRD3 | P35462 | 1/20 | 0.34 |
| ▸ | XDH | P47989 | 1/20 | 0.34 |
| ▸ | LRRK2 | Q5S007 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL42314 | 0.79 | ADORA2A (0.66) | NUDT1ADORA2AADORA1ALDH1A1PI4KA | |
| SCHEMBL5490464 | 0.76 | KDM4E (0.44) | NUDT1ADORA2AADORA1PNPKDM4E | |
| SCHEMBL5667619 | 0.76 | ADORA2A (0.43) | NUDT1ADORA2AADORA1PNPKDM4E | |
| SCHEMBL1868817 | 0.76 | ADORA2A (0.43) | NUDT1ADORA2AADORA1PNPKDM4E | |
| SCHEMBL6831171 | 0.76 | ADORA2A (0.52) | NUDT1ADORA2AADORA1PNPKDM4E | |
| SCHEMBL6829681 | 0.76 | ADORA2A (0.43) | NUDT1ADORA2AADORA1PNPKDM4E | |
| SCHEMBL6826186 | 0.73 | ALDH1A1 (0.35) | NUDT1ADORA2AADORA1PNPKDM4E | |
| SCHEMBL9850315 | 0.72 | NUDT1 (0.40) | NUDT1ADORA2AADORA1PNPKDM4E | |
| SCHEMBL30962317 | 0.68 | ADORA2A (0.61) | NUDT1ADORA2AADORA1ALDH1A1PI4KA | |
| SCHEMBL843217 | 0.68 | ADORA2A (0.61) | NUDT1ADORA2AADORA1ALDH1A1PI4KA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20040214198-A1 | Allele-targeted RNA interference | UNIVERSITY OF MASSACHUSETTS | 2004-10-28 | — | — | US | disclosed |
| WO-2004046324-A2 | ALLELE-TARGETED RNA INTERFERENCE | UNIVERSITY OF MASSACHUSETTS (US) | 2004-06-03 | — | — | WO | disclosed |