SCHEMBL320848

SCHEMBL320848

Cc1ncnc2nc(N)[nH]c12

nearest known ligand 0.46

Predicted protein targets (top 18)

geneUniProtsupporting neighboursconfidence
NUDT1 P36639 4/20 0.43
ADORA2A P29274 1/20 0.43
ADORA1 P30542 1/20 0.43
PNP P00491 2/20 0.42
KDM4E B2RXH2 1/20 0.41
MEN1 O00255 1/20 0.41
ALDH1A1 P00352 1/20 0.41
MAPT P10636 1/20 0.41
THRB P10828 1/20 0.41
HPGD P15428 1/20 0.41
KMT2A Q03164 1/20 0.41
HSD17B10 Q99714 1/20 0.41
CYP1A2 P05177 1/20 0.39
PI4KA P42356 5/20 0.38
PI4K2B Q8TCG2 5/20 0.38
PI4K2A Q9BTU6 5/20 0.38
PI4KB Q9UBF8 5/20 0.38
AKT2 P31751 1/20 0.36

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL30534246 0.81 AKT2 (0.46) NUDT1ADORA2AADORA1MAPTPI4KA
SCHEMBL29400753 0.79 ADORA2A (0.66) NUDT1ADORA2AADORA1ALDH1A1PI4KA
SCHEMBL42314 0.79 ADORA2A (0.66) NUDT1ADORA2AADORA1ALDH1A1PI4KA
SCHEMBL6831171 0.76 ADORA2A (0.52) NUDT1ADORA2AADORA1PNPKDM4E
SCHEMBL1868817 0.76 ADORA2A (0.43) NUDT1ADORA2AADORA1PNPKDM4E
SCHEMBL6829681 0.76 ADORA2A (0.43) NUDT1ADORA2AADORA1PNPKDM4E
SCHEMBL5667619 0.76 ADORA2A (0.43) NUDT1ADORA2AADORA1PNPKDM4E
SCHEMBL6826187 0.76 NUDT1 (0.44) NUDT1ADORA2AADORA1PNPKDM4E
SCHEMBL6360434 0.76 NUDT1 (0.36) NUDT1ADORA2AADORA1PI4KAPI4K2B
SCHEMBL5490464 0.76 KDM4E (0.44) NUDT1ADORA2AADORA1PNPKDM4E

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 84 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-6620599-B1 Inoculating plants in cultures and mixtures comprising auxins and cytokinins, then incubating, extracting in solvents and filtering to obtain flavonoids COUNCIL OF SCIENTIFIC AND INDUSTRIAL RESEARCH (IN) 2003-09-16 US claimed
US-6365757-B1 CULTURING TISSUES OF TAXUS WALLICHIANIA; ISOLATION BY PARTITIONING THE CULTURE PRODUCT RESIDUE, OBTAINED BY POLAR SOLVENT EXTRACTION; DESOLVENTIZING BETWEEN WATER AND CHLORINATED SOLVENTS; EVAPORATION; CHROMOTOGRAPHY; ADSORPTION; COUNCIL OF SCIENTIFIC AND INDUSTRIAL RESEARCH (IN) 2002-04-02 US claimed
US-20250059537-A1 THERAPEUTIC OLIGONUCLEOTIDES HAVING AN INTER-NUCLEOSIDE AMIDE LINKAGE OXFORD UNIVERSITY INNOVATION LIMITED (GB) 2025-02-20 US disclosed
EP-4448541-A1 THERAPEUTIC OLIGONUCLEOTIDES HAVING AN INTER-NUCLEOSIDE AMIDE LINKAGE Oxford University Innovation Limited (GB) 2024-10-23 EP disclosed
WO-2023111597-A1 THERAPEUTIC OLIGONUCLEOTIDES HAVING AN INTER-NUCLEOSIDE AMIDE LINKAGE OXFORD UNIVERSITY INNOVATION LIMITED (GB) 2023-06-22 WO disclosed
WO-2022268932-A1 SYSTEMS AND METHODS FOR SINGLE CELL ANALYSIS THERMO FISHER SCIENTIFIC GENEART GMBH (DE) 2022-12-29 WO disclosed
EP-3469009-B1 SOLID SUPPORT LIFE TECH AS (NO) 2022-04-13 EP disclosed
US-11041068-B2 Solid support LIFE TECHNOLOGIES AS (NO) 2021-06-22 US disclosed
US-20190264017-A1 SOLID SUPPORT LIFE TECHNOLOGIES AS (NO) 2019-08-29 US disclosed
EP-3469009-A1 SOLID SUPPORT Life Technologies AS (NO) 2019-04-17 EP disclosed
US-20180135099-A1 NANOREPORTERS AND METHODS OF MANUFACTURING AND USE THEREOF NANOSTRING TECHNOLOGIES, INC. 2018-05-17 US disclosed
US-20020182602-A1 Mobility-modified nucleobase polymers and methods of using same APPLIED BIOSYSTEMS, INC. 2002-12-05 US disclosed
WO-2002083954-A1 MOBILITY-MODIFIED NUCLEOBASE POLYMERS AND METHODS OF USING SAME APPLERA CORPORATION (US) 2002-10-24 WO disclosed
WO-2002079516-A1 NUCLEIC ACID ANALYSIS USING NON-TEMPLATED NUCLEOTIDE ADDITION APPLERA CORPORATION (US) 2002-10-10 WO disclosed
US-20020142342-A1 Nucleic acid analysis using non-templated nucleotide addition PE CORPORATION (NY) (US) 2002-10-03 US disclosed
US-6365757-B1 CULTURING TISSUES OF TAXUS WALLICHIANIA; ISOLATION BY PARTITIONING THE CULTURE PRODUCT RESIDUE, OBTAINED BY POLAR SOLVENT EXTRACTION; DESOLVENTIZING BETWEEN WATER AND CHLORINATED SOLVENTS; EVAPORATION; CHROMOTOGRAPHY; ADSORPTION; COUNCIL OF SCIENTIFIC AND INDUSTRIAL RESEARCH (IN) 2002-04-02 US disclosed
WO-2002010182-A2 METHODS FOR ISOLATING ONE STRAND OF A DOUBLE-STRANDED NUCLEIC ACID APPLERA CORPORATION (US) 2002-02-07 WO disclosed
EP-1148947-A1 FIBRE ARRAY FOR CONTACTING CHEMICAL SPECIES AND METHODS FOR USING AND MAKING SAME PE Corporation (NY) (US) 2001-10-31 EP disclosed
WO-2000040334-A1 FIBER ARRAY FOR CONTACTING CHEMICAL SPECIES AND METHODS FOR USING AND MAKING SAME PE CORPORATION (NY) (US) 2000-07-13 WO disclosed
WO-1999060170-A1 LINEAR ARRAYS OF IMMOBILIZED COMPOUNDS AND METHODS OF USING SAME HYSEQ, INC. (US) 1999-11-25 WO disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20020182602-A1 Mobility-modified nucleobase polymers and methods of using same PCNA, PNKP, SAMHD1 NUDT1 56/4885ADORA2A 1620/4885ADORA1 2191/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.