Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | FPR2 | P25090 | 3/20 | 0.55 |
| ▸ | BRAF | P15056 | 1/20 | 0.50 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.50 |
| ▸ | MAPT | P10636 | 3/20 | 0.47 |
| ▸ | SMN1; SMN2 | Q16637 | 4/20 | 0.46 |
| ▸ | RAB9A | P51151 | 3/20 | 0.46 |
| ▸ | NPC1 | O15118 | 2/20 | 0.46 |
| ▸ | MEN1 | O00255 | 3/20 | 0.45 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.45 |
| ▸ | NAMPT | P43490 | 2/20 | 0.45 |
| ▸ | CASR | P41180 | 1/20 | 0.44 |
| ▸ | TP53 | P04637 | 2/20 | 0.44 |
| ▸ | POLB | P06746 | 2/20 | 0.44 |
| ▸ | TSHR | P16473 | 2/20 | 0.44 |
| ▸ | PKM | P14618 | 1/20 | 0.43 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.43 |
| ▸ | SAE1 | Q9UBE0 | 1/20 | 0.43 |
| ▸ | UBA2 | Q9UBT2 | 1/20 | 0.43 |
| ▸ | LMNA | P02545 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL18689321 | 0.83 | FPR2 (0.56) | FPR2MEN1KMT2ANAMPT | |
| SCHEMBL19859837 | 0.75 | NAMPT (0.44) | FPR2SMN1; SMN2NAMPTKDM4E | |
| SCHEMBL21669959 | 0.72 | FPR2 (0.58) | FPR2MAPTSMN1; SMN2RAB9ANPC1 | |
| SCHEMBL21669954 | 0.71 | FPR2 (1.00) | FPR2BRAFHDAC1MAPTSMN1; SMN2 | |
| SCHEMBL17286120 | 0.71 | FPR2 (1.00) | FPR2BRAFHDAC1MAPTSMN1; SMN2 | |
| SCHEMBL30797089 | 0.71 | RAB9A (0.64) | FPR2MAPTSMN1; SMN2RAB9ANPC1 | |
| SCHEMBL2470672 | 0.69 | TAAR1 (0.64) | FPR2MAPTSMN1; SMN2RAB9ANPC1 | |
| SCHEMBL2430777 | 0.68 | CASR (0.76) | FPR2MAPTSMN1; SMN2RAB9ANPC1 | |
| SCHEMBL19473728 | 0.68 | ANPEP (0.56) | FPR2MAPTSMN1; SMN2RAB9ANPC1 | |
| SCHEMBL19473726 | 0.68 | ANPEP (0.56) | FPR2MAPTSMN1; SMN2RAB9ANPC1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-10800744-B2 | Imidazole derivatives as formyl peptide receptor modulators | ALLERGAN, INC. (US) | 2020-10-13 | — | — | US | disclosed |
| US-20200115346-A1 | IMIDAZOLE DERIVATIVES AS FORMYL PEPTIDE RECEPTOR MODULATORS | ALLERGAN INC (US) | 2020-04-16 | — | — | US | disclosed |
| EP-3145916-B1 | IMIDAZOLE DERIVATIVES AS FORMYL PEPTIDE RECEPTOR MODULATORS | ALLERGAN INC (US) | 2020-02-12 | — | — | EP | disclosed |
| US-10301269-B2 | Imidazole derivatives as formyl peptide receptor modulators | ALLERGAN, INC. (US) | 2019-05-28 | — | — | US | disclosed |
| US-20170096401-A1 | IMIDAZOLE DERIVATIVES AS FORMYL PEPTIDE RECEPTOR MODULATORS | ALLERGAN, INC. | 2017-04-06 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (4 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20200115346-A1 | IMIDAZOLE DERIVATIVES AS FORMYL PEPTIDE RECEPTOR MODULATORS | FPR1, FPR3, FPR2 | FPR2 3/4885BRAF 1694/4885HDAC1 1788/4885 |
| US-20170096401-A1 | IMIDAZOLE DERIVATIVES AS FORMYL PEPTIDE RECEPTOR MODULATORS | FPR1, FPR3, FPR2 | FPR2 3/4885BRAF 1694/4885HDAC1 1788/4885 |
| US-10301269-B2 | Imidazole derivatives as formyl peptide receptor modulators | FPR1, FPR3, FPR2 | FPR2 3/4885BRAF 1694/4885HDAC1 1788/4885 |
| US-10800744-B2 | Imidazole derivatives as formyl peptide receptor modulators | FPR1, FPR3, FPR2 | FPR2 3/4885BRAF 1694/4885HDAC1 1788/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.