SCHEMBL186971

SCHEMBL186971

Cc1cc(-c2ccc(N)cc2)c(C)c(C)c1N

nearest known ligand 0.49

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
POLB P06746 1/20 0.41
CYP3A4 P08684 5/20 0.41
ALDH1A1 P00352 4/20 0.41
TDP1 Q9NUW8 4/20 0.41
TSHR P16473 3/20 0.41
TP53 P04637 2/20 0.41
DHFR P00374 1/20 0.40
RPS6KA3 P51812 1/20 0.38
ACHE P22303 1/20 0.37
CASP1 P29466 2/20 0.37
CA12 O43570 1/20 0.36
CA9 Q16790 1/20 0.36
MAOB P27338 2/20 0.36
MAOA P21397 1/20 0.35
TAAR1 Q96RJ0 1/20 0.34
HSD17B10 Q99714 1/20 0.34
PDE10A Q9Y233 1/20 0.34
TNKS O95271 1/20 0.34
PARP1 P09874 1/20 0.34
TNKS2 Q9H2K2 1/20 0.34

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL28211221 0.85 CYP3A4 (0.42) CYP3A4ALDH1A1TDP1TSHRTP53
SCHEMBL28754177 0.83 PDE4A (0.44) POLBCYP3A4ALDH1A1TDP1TSHR
Hydrochloric Acid SCHEMBL28477097 0.82 PDE4A (0.43) POLBCYP3A4ALDH1A1TDP1TSHR
SCHEMBL8778197 0.80 ALDH1A1 (0.59) POLBCYP3A4ALDH1A1TDP1TSHR
SCHEMBL27904270 0.80 ALDH1A1 (0.59) POLBCYP3A4ALDH1A1TDP1TSHR
SCHEMBL8954074 0.80 DHFR (0.55) CYP3A4ALDH1A1TDP1TSHRTP53
SCHEMBL19551144 0.79 POLB (0.48) POLBCYP3A4ALDH1A1TDP1TSHR
SCHEMBL28853371 0.79 CYP3A4 (0.39) CYP3A4ALDH1A1TDP1TSHRTP53
SCHEMBL27838382 0.79 HSD17B10 (0.50) POLBCYP3A4ALDH1A1TDP1TP53
SCHEMBL9324203 0.78 ALDH1A1 (0.46) POLBCYP3A4ALDH1A1TDP1TSHR

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 222 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-114716676-A Application of polyimide in gas separation membrane 浙江工业大学 2022-07-08 CN claimed
CN-111057260-A Preparation method of black matte polyimide film 株洲时代华鑫新材料技术有限公司 2020-04-24 CN claimed
US-20140113316-A1 DEVICE, METHOD AND KIT FOR THE DETECTION OF DIFFERENT MARKERS IN DIFFERENT CELLULAR OR MOLECULAR TYPES AND THEIR QUANTIFICATIONS MAZZEO ALESSANDRA (IT) 2014-04-24 US claimed
JP-63091563-A None JP disclosed
US-20260035414-A1 HERV-K (HML-2) ENV ANALOG FUSION PROTEINS FOR ANTIGEN SPECIFIC IMMUNOTHERAPY AND METHODS OF USE UNITED STATES GOVERNMENT 2026-02-05 US disclosed
US-20260035415-A1 HERV-K (HML-2) ENV ANALOG FUSION PROTEINS FOR ANTIGEN SPECIFIC IMMUNOTHERAPY AND METHODS OF USE UNITED STATES GOVERNMENT 2026-02-05 US disclosed
US-20260035433-A1 PD-L1 ANALOG FUSION PROTEINS FOR ANTIGEN SPECIFIC IMMUNOTHERAPY AND METHODS OF USE AKSTON BIOSCIENCES CORP (US) 2026-02-05 US disclosed
EP-4676530-A2 NUCLEOCAPSID ANTIGEN IMMUNOTHERAPY FOR COVID-19 FUSION PROTEINS AND METHODS OF USE Vakston, Inc. (US) 2026-01-14 EP disclosed
US-12454565-B2 PD-L1 analog fusion proteins for antigen specific immunotherapy and methods of use AKSTON BIOSCIENCES CORPORATION (US) 2025-10-28 US disclosed
US-20250296978-A1 PD-L1 ANALOG FUSION PROTEINS FOR ANTIGEN SPECIFIC IMMUNOTHERAPY AND METHODS OF USE AKSTON BIOSCIENCES CORPORATION 2025-09-25 US disclosed
WO-2024186803-A2 NUCLEOCAPSID ANTIGEN IMMUNOTHERAPY FOR COVID-19 FUSION PROTEINS AND METHODS OF USE AKSTON BIOSCIENCES CORPORATION (US) 2024-09-12 WO disclosed
CN-1165299-A Immunoassay for helicobacter pylori in fecal specimens MERIDIAN DIAGNOSTICS INC (US) 1997-11-19 CN disclosed
EP-0806667-A1 Immunoassay for h. pylori in fecal specimens MERIDIAN DIAGNOSTICS, INC. (US) 1997-11-12 EP disclosed
WO-1997017984-A1 OLIGODENDROCYTE-SPECIFIC PROTEIN AND METHOD FOR TREATING DISEASE RESEARCH GENETICS, INC. (US) 1997-05-22 WO disclosed
EP-0407172-B1 Aromatic polyimide separation membrane MITSUBISHI CHEM IND (JP) 1994-02-23 EP disclosed
WO-1994002648-A1 GAP-FILLING NUCLEIC ACID AMPLIFICATION AND DETECTION IMCLONE SYSTEMS INCORPORATED (US) 1994-02-03 WO disclosed
US-5112941-A A fluorinated membranes with high selectivity MITSUBISHI KASEI CORPORATION (JP) 1992-05-12 US disclosed
EP-0180564-B1 IMMUNOGENIC COMPLEX, A METHOD FOR PRODUCING THE SAME, AND THE USE THEREOF AS AN IMMUNE STIMULANT, VACCINES AND REAGENTS Morein, Bror (SE) 1991-07-17 EP disclosed
EP-0407172-A1 Aromatic polyimide separation membrane MITSUBISHI KASEI CORPORATION (JP) 1991-01-09 EP disclosed
JP-S6391563-A EXAMINATION OF PROTEIN SPECIFIC ANTIGEN DERIVED FROM BACTERIA NITSUSUI SEIYAKU KK 1988-04-22 JP disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (3 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20260035415-A1 HERV-K (HML-2) ENV ANALOG FUSION PROTEINS FOR ANTIGEN SPECIFIC IMMUNOTHERAPY AND METHODS OF USE HM13, MYOF, SMN1; SMN2 POLB 3069/4885CYP3A4 4818/4885ALDH1A1 4843/4885
US-20260035433-A1 PD-L1 ANALOG FUSION PROTEINS FOR ANTIGEN SPECIFIC IMMUNOTHERAPY AND METHODS OF USE PDCD1LG2, CD274, PDCD1 POLB 4281/4885CYP3A4 4698/4885ALDH1A1 3953/4885
US-20260035414-A1 HERV-K (HML-2) ENV ANALOG FUSION PROTEINS FOR ANTIGEN SPECIFIC IMMUNOTHERAPY AND METHODS OF USE SMN1; SMN2, FUS, MORF4L1 POLB 3105/4885CYP3A4 4844/4885ALDH1A1 4845/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.