SCHEMBL18697264

SCHEMBL18697264

CC1(C)CC2(CC(C)(C)N1Oc1ccccc1)OC(=O)N(c1ccccc1)C2=O

nearest known ligand 0.42

Predicted protein targets (top 17)

geneUniProtsupporting neighboursconfidence
ELANE P08246 4/20 0.35
CACNA1B Q00975 1/20 0.35
APBA1 Q02410 1/20 0.35
HSD11B1 P28845 1/20 0.34
PGR P06401 2/20 0.33
MAOA P21397 1/20 0.33
ALDH1A1 P00352 3/20 0.32
AR P10275 1/20 0.32
LMNA P02545 1/20 0.31
HPGD P15428 1/20 0.31
CYP1A2 P05177 1/20 0.31
CYP2C9 P11712 1/20 0.31
CYP2C19 P33261 1/20 0.31
CTSG P08311 1/20 0.31
PRTN3 P24158 1/20 0.31
MGLL Q99685 1/20 0.31
GRM2 Q14416 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL10124675 0.87 ELANE (0.36) ELANECACNA1BAPBA1HSD11B1PGR
SCHEMBL10124677 0.84 ELANE (0.39) ELANECACNA1BAPBA1HSD11B1PGR
SCHEMBL10124680 0.81 ELANE (0.38) ELANECACNA1BAPBA1HSD11B1PGR
SCHEMBL10124678 0.81 CACNA1B (0.35) ELANECACNA1BAPBA1HSD11B1PGR
SCHEMBL18697204 0.80 ALDH1A1 (0.35) ELANECACNA1BAPBA1HSD11B1PGR
SCHEMBL10124682 0.78 ELANE (0.38) ELANEALDH1A1LMNAHPGDCYP2C9
SCHEMBL10124681 0.78 ELANE (0.38) ELANEALDH1A1LMNAHPGDCYP2C9
SCHEMBL18697263 0.76 POLB (0.40) ELANECACNA1BAPBA1PGRALDH1A1
SCHEMBL11376669 0.74 ELANE (0.42) ELANECACNA1BAPBA1HSD11B1MAOA
SCHEMBL13050166 0.72 TRIP13 (0.38) ALDH1A1ARHPGDMGLL

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-2440557-B1 NOVEL STERICALLY HINDERED AMINE LIGHT STABILIZERS BASF SE (DE) 2017-04-05 EP disclosed