SCHEMBL18697294

SCHEMBL18697294

O=C(F)Oc1cccc(Cl)c1

nearest known ligand 0.53

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
BCHE P06276 1/20 0.53
OGG1 O15527 1/20 0.46
MEN1 O00255 1/20 0.45
KMT2A Q03164 1/20 0.45
MAOB P27338 1/20 0.45
AOC3 Q16853 1/20 0.45
RXRA P19793 1/20 0.45
RXRB P28702 1/20 0.45
RXRG P48443 1/20 0.45
FFAR1 O14842 1/20 0.44
PPARG P37231 1/20 0.44
PPARD Q03181 1/20 0.44
KDM4E B2RXH2 3/20 0.44
USP2 O75604 1/20 0.44
ALDH1A1 P00352 1/20 0.44
ALOX15 P16050 1/20 0.44
NPSR1 Q6W5P4 1/20 0.44
WDR5 P61964 1/20 0.43
FAAH O00519 1/20 0.43
PARP1 P09874 1/20 0.42

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL18697308 0.85 KMT2A (0.60) BCHEMEN1KMT2ANPSR1
SCHEMBL5916715 0.83 BCHE (0.51) BCHEOGG1MEN1KMT2ARXRA
SCHEMBL7932475 0.83 BCHE (0.51) BCHEOGG1MEN1KMT2ARXRA
SCHEMBL4344412 0.82 BCHE (0.50) BCHEOGG1MEN1KMT2ARXRA
SCHEMBL9671217 0.82 RXRA (0.50) BCHEOGG1MEN1KMT2ARXRA
SCHEMBL3884023 0.82 BCHE (0.50) BCHEOGG1MEN1KMT2ARXRA
SCHEMBL9671211 0.82 BCHE (0.50) BCHEOGG1MEN1KMT2ARXRA
SCHEMBL337714 0.80 CYP3A4 (0.63) BCHEOGG1MEN1KMT2AMAOB
SCHEMBL4344418 0.80 MEN1 (0.73) BCHEOGG1MEN1KMT2ARXRA
SCHEMBL20296798 0.79 OGG1 (0.46) BCHEOGG1MEN1KMT2ARXRA

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20170194664-A1 NONAQUEOUS ELECTROLYTE AND ELECTRICITY STORING DEVICE IN WHICH SAME IS USED MU IONIC SOLUTIONS CORPORATION (JP) 2017-07-06 US disclosed
US-20170194664-A1 NONAQUEOUS ELECTROLYTE AND ELECTRICITY STORING DEVICE IN WHICH SAME IS USED MU IONIC SOLUTIONS CORPORATION (JP) 2017-07-06 US disclosed
EP-3151326-A1 NONAQUEOUS ELECTROLYTE AND ELECTRICITY-STORING DEVICE IN WHICH SAME IS USED Ube Industries, Ltd. (JP) 2017-04-05 EP disclosed