SCHEMBL18697308

SCHEMBL18697308

O=C(F)Oc1cccc(OC(=O)F)c1

nearest known ligand 0.60

Predicted protein targets (top 18)

geneUniProtsupporting neighboursconfidence
KMT2A Q03164 2/20 0.60
MEN1 O00255 1/20 0.60
NPC1 O15118 1/20 0.52
RAB9A P51151 1/20 0.52
NPSR1 Q6W5P4 1/20 0.52
LMNA P02545 2/20 0.47
CYP3A4 P08684 1/20 0.47
ACHE P22303 4/20 0.42
ESR1 P03372 1/20 0.42
ESR2 Q92731 1/20 0.42
BCHE P06276 2/20 0.40
NSD2 O96028 1/20 0.39
CYP1A2 P05177 1/20 0.39
MAPT P10636 1/20 0.39
CYP2C19 P33261 1/20 0.39
CES2 O00748 1/20 0.39
CES1 P23141 1/20 0.39
SERPINE1 P05121 1/20 0.39

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL18697278 0.87 ESR1 (0.53) KMT2AMEN1NPC1RAB9ANPSR1
SCHEMBL18697294 0.85 BCHE (0.53) KMT2AMEN1NPSR1BCHE
SCHEMBL18697271 0.85 LMNA (0.69) KMT2AMEN1RAB9ALMNACYP3A4
SCHEMBL7519309 0.82 TDP1 (0.50) RAB9ABCHENSD2MAPT
SCHEMBL18697300 0.82 PRSS1 (0.54) NPSR1LMNAMAPTCES2
SCHEMBL18697297 0.80 ACHE (0.49) KMT2AMEN1LMNACYP3A4ACHE
SCHEMBL7937746 0.79 F2 (0.60) KMT2AMEN1LMNAMAPTCES2
SCHEMBL18686712 0.78 RAB9A (0.46) KMT2AMEN1RAB9ALMNAESR1
SCHEMBL1040127 0.77 KMT2A (0.62) KMT2AMEN1NPC1RAB9ANPSR1
SCHEMBL18697358 0.76 CES2 (0.46) KMT2AMEN1NPC1RAB9ANPSR1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20170194664-A1 NONAQUEOUS ELECTROLYTE AND ELECTRICITY STORING DEVICE IN WHICH SAME IS USED MU IONIC SOLUTIONS CORPORATION (JP) 2017-07-06 US disclosed
US-20170194664-A1 NONAQUEOUS ELECTROLYTE AND ELECTRICITY STORING DEVICE IN WHICH SAME IS USED MU IONIC SOLUTIONS CORPORATION (JP) 2017-07-06 US disclosed
EP-3151326-A1 NONAQUEOUS ELECTROLYTE AND ELECTRICITY-STORING DEVICE IN WHICH SAME IS USED Ube Industries, Ltd. (JP) 2017-04-05 EP disclosed