Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TAAR1 | Q96RJ0 | 2/20 | 0.33 |
| ▸ | MEN1 | O00255 | 1/20 | 0.31 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.31 |
| ▸ | PLA2G1B | P04054 | 1/20 | 0.31 |
| ▸ | HSP90AA1 | P07900 | 1/20 | 0.31 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.31 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.31 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.31 |
| ▸ | HPGD | P15428 | 1/20 | 0.31 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.31 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.31 |
| ▸ | HTT | P42858 | 1/20 | 0.31 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.31 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.31 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.31 |
| ▸ | ATG4B | Q9Y4P1 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL29293325 | 0.77 | PLA2G1B (0.33) | TAAR1MEN1ALDH1A1PLA2G1BHSP90AA1 | |
| SCHEMBL10282138 | 0.75 | HPGD (0.36) | MEN1ALDH1A1PLA2G1BHSP90AA1CYP3A4 | |
| SCHEMBL22791315 | 0.69 | CCR2 (0.35) | MEN1ALDH1A1PLA2G1BHSP90AA1CYP3A4 | |
| SCHEMBL22791569 | 0.65 | GAA (0.35) | MEN1ALDH1A1CYP3A4HPGDKMT2A | |
| SCHEMBL25057042 | 0.65 | TRPA1 (0.34) | MEN1ALDH1A1KMT2A | |
| SCHEMBL19540597 | 0.61 | ALDH1A1 (0.50) | MEN1ALDH1A1CYP3A4HPGDCYP2C19 | |
| SCHEMBL20274096 | 0.61 | MEN1 (0.37) | MEN1ALDH1A1CYP3A4HPGDCYP2C19 | |
| SCHEMBL22791443 | 0.59 | SLC6A4 (0.31) | — | |
| SCHEMBL29293276 | 0.59 | TAAR1 (0.49) | TAAR1 | |
| SCHEMBL7751782 | 0.59 | TDP1 (0.40) | MEN1ALDH1A1PLA2G1BCYP3A4CYP2D6 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3735411-B1 | 1,3,4,5-TETRAHYDRO-2H-PYRIDO[4,3-B]INDOLE DERIVATIVES FOR THE TREATMENT, ALLEVIATION OR PREVENTION OF DISORDERS ASSOCIATED WITH TAU AGGREGATES LIKE ALZHEIMER`S DISEASE | AC IMMUNE SA (CH) | 2024-07-10 | — | — | EP | disclosed |
| EP-3150705-A1 | METHOD FOR INDUCING MYOCARDIAL DIFFERENTIATION OF PLURIPOTENT STEM CELLS USING LOW-MOLECULAR COMPOUND | Kyoto University (JP) | 2017-04-05 | — | — | EP | disclosed |