SCHEMBL18700985

SCHEMBL18700985

CCc1ccc(S(=O)(=O)O)c(OC)c1C

nearest known ligand 0.36

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
LMNA P02545 2/20 0.35
HSD17B10 Q99714 2/20 0.35
HIF1A Q16665 2/20 0.35
HPGD P15428 1/20 0.35
SLC2A1 P11166 1/20 0.35
SMN1; SMN2 Q16637 3/20 0.34
METAP2 P50579 2/20 0.34
ALDH1A1 P00352 4/20 0.33
TP53 P04637 1/20 0.33
MAPT P10636 1/20 0.33
CHRM2 P08172 1/20 0.32
CHRM1 P11229 1/20 0.32
RRM1 P23921 1/20 0.32
RRM2B Q7LG56 1/20 0.32
TSHR P16473 1/20 0.31
CASP1 P29466 1/20 0.31
CASP7 P55210 1/20 0.31
MEN1 O00255 1/20 0.31
CYP1A2 P05177 1/20 0.31
GLA P06280 1/20 0.31

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL18700944 0.80 ALDH1A1 (0.39) LMNAHSD17B10HIF1ASMN1; SMN2ALDH1A1
SCHEMBL9014150 0.80 MEN1 (0.37) LMNAHSD17B10HIF1AHPGDMETAP2
SCHEMBL25340129 0.78 SMN1; SMN2 (0.33) LMNAHSD17B10HIF1AHPGDSLC2A1
SCHEMBL18700968 0.77 GABRA1 (0.41) LMNAHSD17B10SLC2A1SMN1; SMN2METAP2
SCHEMBL12797852 0.77 PTGS2 (0.37) SMN1; SMN2METAP2ALDH1A1MAPTTSHR
SCHEMBL11308691 0.74 ALOX5 (0.42) ALDH1A1TP53MAPTTSHRMEN1
SCHEMBL19463402 0.74 TRPV1 (0.41)
SCHEMBL27017209 0.74 ALDH1A1 (0.35) LMNASMN1; SMN2ALDH1A1MAPTTSHR
SCHEMBL5167659 0.72 SLC2A1 (0.31) SLC2A1
SCHEMBL13067434 0.72 SMN1; SMN2 (0.44) LMNASMN1; SMN2ALDH1A1MAPTCHRM2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-3359620-B1 METHOD OF MONITORING A PARAMETER OF A HYDROCARBON WELL, PIPELINE OR FORMATION JOHNSON MATTHEY PLC (GB) 2022-11-30 EP disclosed
US-10365262-B2 Method of monitoring a parameter of a hydrocarbon well, pipeline or formation JOHNSON MATTHEY PUBLIC LIMITED COMPANY (GB) 2019-07-30 US disclosed
US-20180284096-A1 METHOD OF MONITORING A PARAMETER OF A HYDROCARBON WELL, PIPELINE OR FORMATION TRACERCO LIMITED (GB) 2018-10-04 US disclosed
WO-2017060702-A1 METHOD OF MONITORING A PARAMETER OF A HYDROCARBON WELL, PIPELINE OR FORMATION JOHNSON MATTHEY PUBLIC LIMITED COMPANY (GB) 2017-04-13 WO disclosed