Known targets — ChEMBL curated mechanism
ABCC8ACEADORA1ADORA2AADORA2BADORA3ALDH5A1ALOX5ALOX5APATP4AATP4BBRAFCA1CA12CA2CA4CYSLTR1DHFRDPEP1EDNRAEDNRBESR2F10FDPSFGF1GABBR1GABBR2GABRA1GABRA2GABRA3GABRA4GABRA5GABRA6GABRB1GABRB2GABRB3GABRDGABREGABRG1GABRG2GABRG3GABRPGABRQGARTGNRHRGSC1HMGCRIMPDH1IMPDH2KCNJ11LY96NOD2NR3C1NS3NS4ANS5bP2RY1P2RY12P2RY2P2RY4P2RY6PBP2XPDE3APDE3BPDE4APDE4BPDE4CPDE4DPDK1PDK2PDK3PDK4PPARGPPATPTGIRPTGS1PTGS2RAF1RYR1RYR3SCN10ASCN11ASCN1ASCN2ASCN3ASCN4ASCN5ASCN7ASCN8ASCN9ASERPINC1SLC12A1SLC12A3SYKTHRATHRBTLR3TLR4TLR9TUBA1ATUBA1BTUBA1CTUBA3CTUBA3ETUBA4ATUBBTUBB1TUBB2ATUBB2BTUBB3TUBB4ATUBB4BTUBB6TUBB8TYMSVKORC1XDHblablaIMP-1blaOXA-33blaOXA-58blaT-3blaT-4blaT-5blaT-6dacAdacBdacCfolAfolPfolP1ftsIfusAgaggyrAgyrBmecAmrcAmrcBmrdApbp1apbp1bpbp2pbp2apbp2bpbp3pbp4pbpApbpBpbpCpbpFpolponBrplArplBrplCrplDrplErplFrplJrplKrplLrplMrplNrplOrplPrplQrplRrplSrplTrplUrplVrplWrplXrplYrpmArpmBrpmCrpmDrpmErpmFrpmGrpmHrpmIrpmJrpoArpoBrpoCrpoZrpsArpsBrpsCrpsDrpsErpsFrpsGrpsHrpsIrpsJrpsKrpsLrpsMrpsNrpsOrpsPrpsQrpsRrpsSrpsTrpsUykgMykgO
The experimentally established mechanism targets of None. The predicted profile below is derived independently by chemical similarity — agreement is a validation signal, a miss is honest.
Predicted protein targets (top 1)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SLC2A1 | P11166 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL25340129 | 0.81 | SMN1; SMN2 (0.33) | SLC2A1 | |
| SCHEMBL18700985 | 0.72 | LMNA (0.35) | SLC2A1 | |
| SCHEMBL18700968 | 0.70 | GABRA1 (0.41) | SLC2A1 | |
| SCHEMBL11308691 | 0.68 | ALOX5 (0.42) | — | |
| SCHEMBL7269471 | 0.67 | MAPT (0.46) | — | |
| SCHEMBL18700944 | 0.66 | ALDH1A1 (0.39) | — | |
| SCHEMBL28477669 | 0.66 | ALDH1A1 (0.38) | — | |
| SCHEMBL9822579 | 0.65 | LMNA (0.36) | — | |
| SCHEMBL18700993 | 0.65 | TET2 (0.36) | — | |
| SCHEMBL24094066 | 0.65 | SMN1; SMN2 (0.35) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1773916-B1 | PROCESS FOR PREPARATION OF FUNCTIONALIZED POLYIMIDES | SABIC INNOVATIVE PLASTICS IP (NL) | 2014-02-12 | — | — | EP | disclosed |
| EP-1773916-A1 | PROCESS FOR PREPARATION OF FUNCTIONALIZED POLYIMIDES | The General Electric Company (US) | 2007-04-18 | — | — | EP | disclosed |
| US-7148314-B2 | Process for preparation of functionalized polyimides | GENERAL ELECTRIC COMPANY (US) | 2006-12-12 | — | — | US | disclosed |
| WO-2006014448-A1 | PROCESS FOR PREPARATION OF FUNCTIONALIZED POLYIMIDES | GENERAL ELECTRIC COMPANY (US) | 2006-02-09 | — | — | WO | disclosed |
| US-20060009613-A1 | Process for preparation of of functionalized polyimides | GENERAL ELECTRIC COMPANY | 2006-01-12 | — | — | US | disclosed |