Predicted protein targets (top 4)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NISCH | Q9Y2I1 | 17/20 | 0.49 |
| ▸ | TAAR1 | Q96RJ0 | 1/20 | 0.41 |
| ▸ | HTR1D | P28221 | 1/20 | 0.38 |
| ▸ | ADRA1A | P35348 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11300573 | 0.75 | NISCH (0.52) | NISCH | |
| SCHEMBL12226606 | 0.71 | NISCH (0.52) | NISCH | |
| SCHEMBL1273061 | 0.67 | DHODH (0.54) | — | |
| SCHEMBL7208490 | 0.67 | NISCH (0.46) | NISCH | |
| SCHEMBL9579892 | 0.67 | NISCH (0.81) | NISCH | |
| SCHEMBL20772453 | 0.66 | KIF11 (0.41) | — | |
| SCHEMBL16455577 | 0.66 | RPS6KA3 (0.49) | — | |
| SCHEMBL11833135 | 0.66 | NISCH (1.00) | NISCHHTR1DADRA1A | |
| SCHEMBL24208881 | 0.66 | NISCH (0.58) | NISCHHTR1DADRA1A | |
| SCHEMBL8189633 | 0.66 | NISCH (0.71) | NISCHHTR1DADRA1A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3659438-A1 | COMPOUNDS AND COMPOSITIONS HAVING KNOCK-DOWN OR BLOOD FEED INHIBITION ACTIVITY AGAINST INSECT PESTS | SYNGENTA PARTICIPATIONS AG (CH) | 2020-06-03 | — | — | EP | disclosed |
| US-20190350203-A1 | COMPOUNDS AND COMPOSITIONS HAVING KNOCK-DOWN OR BLOOD FEED INHIBITION ACTIVITY AGAINST INSECT PESTS | SYNGENTA PARTICIPATIONS AG (CH) | 2019-11-21 | — | — | US | disclosed |
| US-20170094972-A1 | Compounds and Compositions Having Knock-Down Activity Against Insect Pests | SYNGENTA PARTICIPATIONS AG (CH) | 2017-04-06 | — | — | US | disclosed |
| US-20170094972-A1 | Compounds and Compositions Having Knock-Down Activity Against Insect Pests | SYNGENTA PARTICIPATIONS AG (CH) | 2017-04-06 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20170094972-A1 | Compounds and Compositions Having Knock-Down Activity Against Insect Pests | DDT, AGO2, L3MBTL4 | NISCH 93/4885TAAR1 1974/4885HTR1D 4554/4885 |
| US-20190350203-A1 | COMPOUNDS AND COMPOSITIONS HAVING KNOCK-DOWN OR BLOOD FEED INHIBITION ACTIVITY AGAINST INSECT PESTS | KISS1R, VIP, KDM4E | NISCH 77/4885TAAR1 1499/4885HTR1D 4557/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.