SCHEMBL1870979

SCHEMBL1870979

CC(O)NC(=O)NC(C)O

nearest known ligand 0.39

Predicted protein targets (top 19)

geneUniProtsupporting neighboursconfidence
TP53 P04637 1/20 0.39
FOLH1 Q04609 4/20 0.39
NAALAD2 Q9Y3Q0 2/20 0.39
ALDH1A1 P00352 4/20 0.36
LMNA P02545 2/20 0.36
MEN1 O00255 1/20 0.36
KMT2A Q03164 1/20 0.36
NPC1 O15118 1/20 0.34
RAB9A P51151 1/20 0.34
CA12 O43570 1/20 0.33
CA1 P00915 1/20 0.33
CA2 P00918 1/20 0.33
MMP1 P03956 1/20 0.33
MMP2 P08253 1/20 0.33
MMP9 P14780 1/20 0.33
MMP8 P22894 1/20 0.33
CA9 Q16790 1/20 0.33
TSHR P16473 1/20 0.33
GAA P10253 1/20 0.31

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL20161938 0.84
SCHEMBL18852550 0.80 LMNA (0.44) TP53ALDH1A1LMNACA2
SCHEMBL76689 0.79 TP53 (0.39) TP53ALDH1A1LMNACA12CA1
SCHEMBL4687193 0.78
SCHEMBL82871 0.76
SCHEMBL1345913 0.76
SCHEMBL745482 0.74 ALDH1A1 (0.54) FOLH1NAALAD2ALDH1A1LMNAMEN1
SCHEMBL7096450 0.74 FOLH1 (0.32) TP53FOLH1NAALAD2ALDH1A1LMNA
SCHEMBL8861582 0.73
SCHEMBL27662 0.73

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 20 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-4180631-A Flame-and smoke-resistant flexible polyurethane foam and compressed foam sheet BRIDGESTONE TIRE COMPANY, LIMITED (JP) 1979-12-25 US claimed
US-20110105654-A1 Method for Producing a Compound with at Least One at Least Monosubstituted Amino Group BOREALIS AGROLINZ MELAMINE GMBH (AT) 2011-05-05 US disclosed
US-7671118-B2 Stabilizer system for stabilizing halogen-containing polymers Chemtura Vinyl Additives, GmbH (DE) 2010-03-02 US disclosed
US-20060192179-A1 Novel stabilizer system for stabilizing halogen-containing polymers CROMPTON VINYL ADDITIVES GMBH 2006-08-31 US disclosed
US-7077981-B2 Chlorate-containing stabilizer system with nitrogen-containing synergists for stabilizing halogen-containing polymers CROMPTON VINYL ADDITIVES GMBH (DE) 2006-07-18 US disclosed
US-7070834-B2 Production method of porous medium KONICA MINOLTA PHOTO IMAGING, INC. (JP) 2006-07-04 US disclosed
EP-1498279-A1 Production method of porous medium Konica Minolta Photo Imaging, Inc. (JP) 2005-01-19 EP disclosed
US-20040258845-A1 comprising a non-water-absorptive support and a porous layer provided on the support; includes microparticles of an average primary particle diameter of less than 30 nm, a hydrophilic binder and water onto the support to form a coated layer, drying and applying composition B; ink jets KONICA MINOLTA PHOTO IMAGING, INC. (JP) 2004-12-23 US disclosed
US-20040132875-A1 Chlorate-containing stabilizer system with nitrogen-containing synergists for stabilizing halogen-containing polymers CHEMTURA VINYL ADDITIVES GMBH (DE) 2004-07-08 US disclosed
EP-0490515-B1 Method for preparing lithographic printing plate FUJI PHOTO FILM CO LTD (JP) 1997-10-15 EP disclosed
US-5480762-A Method for preparing lithographic printing plate FUJI PHOTO FILM CO., LTD. (JP) 1996-01-02 US disclosed
EP-0490515-A1 Method for preparing lithographic printing plate FUJI PHOTO FILM CO., LTD. (JP) 1992-06-17 EP disclosed
US-4299782-A FLAME RETARDANT FOR POLYURETHANES PENNWALT CORPORATION (US) 1981-11-10 US disclosed
US-4299782-A FLAME RETARDANT FOR POLYURETHANES PENNWALT CORPORATION (US) 1981-11-10 US disclosed
US-4299782-A FLAME RETARDANT FOR POLYURETHANES PENNWALT CORPORATION (US) 1981-11-10 US disclosed
US-4295846-A FROM UREAS, GLYOXAL, ALCOHOL, ACID BASF AKTIENGESELLSCHAFT (DE) 1981-10-20 US disclosed
US-4246361-A Method for producing flame- and smoke-resistant polyurethane foam sheet by incorporation of a urea derivative in reaction mixture BRIDGESTONE TIRE CO., LTD. (JP) 1981-01-20 US disclosed
US-4216221-A MNEMIC PROCESSES U C B, SOCIETE ANONYME (BE) 1980-08-05 US disclosed
US-4209581-A UREA OR THIOUREA RESIN WITH N-ALKYLOL ACRYLAMIDE TOKYO OHKA KOGYO KABUSHIKI KAISHA (JP) 1980-06-24 US disclosed
US-4180631-A Flame-and smoke-resistant flexible polyurethane foam and compressed foam sheet BRIDGESTONE TIRE COMPANY, LIMITED (JP) 1979-12-25 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20110105654-A1 Method for Producing a Compound with at Least One at Least Monosubstituted Amino Group GNMT, PAM, SMOX TP53 4342/4885FOLH1 1143/4885NAALAD2 1212/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.