Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ATM | Q13315 | 1/20 | 0.66 |
| ▸ | PKM | P14618 | 1/20 | 0.64 |
| ▸ | GPR183 | P32249 | 1/20 | 0.60 |
| ▸ | CTDSP1 | Q9GZU7 | 2/20 | 0.58 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.58 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.58 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.56 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.53 |
| ▸ | GBA1 | P04062 | 1/20 | 0.48 |
| ▸ | HTT | P42858 | 1/20 | 0.47 |
| ▸ | GAA | P10253 | 1/20 | 0.47 |
| ▸ | TSHR | P16473 | 1/20 | 0.47 |
| ▸ | SPR | P35270 | 1/20 | 0.47 |
| ▸ | RORC | P51449 | 1/20 | 0.46 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL29060777 | 0.87 | ATM (0.67) | ATMPKMGPR183CTDSP1TDP1 | |
| SCHEMBL18711915 | 0.82 | ALDH1A1 (0.64) | ATMPKMGPR183CTDSP1TDP1 | |
| SCHEMBL18711516 | 0.81 | ALDH1A1 (0.62) | ALDH1A1 | |
| SCHEMBL1014809 | 0.81 | PKM (0.67) | ATMPKMGPR183CTDSP1TDP1 | |
| SCHEMBL27238533 | 0.80 | ATM (0.58) | ATMPKMGPR183CTDSP1TDP1 | |
| SCHEMBL15830167 | 0.80 | ALDH1A1 (0.53) | ATMTDP1ALDH1A1HTTGAA | |
| SCHEMBL14362536 | 0.79 | TSHR (0.68) | ATMPKMGPR183CTDSP1TDP1 | |
| SCHEMBL18711918 | 0.78 | ALDH1A1 (0.67) | PKMGPR183TDP1ALDH1A1 | |
| SCHEMBL15916798 | 0.78 | GPR183 (0.57) | PKMGPR183KDM4EALDH1A1GBA1 | |
| SCHEMBL12655862 | 0.78 | PKM (0.63) | ATMPKMGPR183CTDSP1TDP1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20170096435-A1 | SEPIAPTERIN REDUCTASE INHIBITORS | MAX-PLANCK-GESELLSCHAFT ZUR FOERDERUNG DER WISSENSCHAFTEN E.V. (DE) | 2017-04-06 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20170096435-A1 | SEPIAPTERIN REDUCTASE INHIBITORS | SPR, QDPR, SRR | ATM 3319/4885PKM 2544/4885GPR183 1543/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.