Known targets — ChEMBL curated mechanism
The experimentally established mechanism targets of Dopamine. The predicted profile below is derived independently by chemical similarity — agreement is a validation signal, a miss is honest.
Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.95 |
| ▸ | MAPT | P10636 | 3/20 | 0.95 |
| ▸ | MAPK1 | P28482 | 3/20 | 0.95 |
| ▸ | TAAR1 | Q96RJ0 | 3/20 | 0.95 |
| ▸ | ADRA2A | P08913 | 2/20 | 0.95 |
| ▸ | DRD2 | P14416 | 2/20 | 0.95 |
| ▸ | DRD1 | P21728 | 2/20 | 0.95 |
| ▸ | DRD4 | P21917 | 2/20 | 0.95 |
| ▸ | DRD5 | P21918 | 2/20 | 0.95 |
| ▸ | SLC6A2 | P23975 | 2/20 | 0.95 |
| ▸ | DRD3 | P35462 | 2/20 | 0.95 |
| ▸ | RECQL | P46063 | 2/20 | 0.95 |
| ▸ | SLC6A3 | Q01959 | 2/20 | 0.95 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.95 |
| ▸ | ALOX15 | P16050 | 2/20 | 0.95 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.95 |
| ▸ | APEX1 | P27695 | 2/20 | 0.95 |
| ▸ | TP53 | P04637 | 1/20 | 0.95 |
| ▸ | ADRB2 | P07550 | 1/20 | 0.95 |
| ▸ | HTR1A | P08908 | 1/20 | 0.95 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Dopamine SCHEMBL28174633 | 0.98 | KDM4E (0.96) | KDM4EMAPTMAPK1TAAR1ADRA2A | |
| Dopamine SCHEMBL16685137 | 0.98 | KDM4E (1.00) | KDM4EMAPTMAPK1TAAR1ADRA2A | |
| Dopamine SCHEMBL496657 | 0.98 | KDM4E (1.00) | KDM4EMAPTMAPK1TAAR1ADRA2A | |
| Dopamine SCHEMBL29362033 | 0.98 | KDM4E (1.00) | KDM4EMAPTMAPK1TAAR1ADRA2A | |
| Dopamine SCHEMBL18159501 | 0.98 | KDM4E (1.00) | KDM4EMAPTMAPK1TAAR1ADRA2A | |
| Dopamine SCHEMBL30379944 | 0.98 | KDM4E (1.00) | KDM4EMAPTMAPK1TAAR1ADRA2A | |
| Dopamine SCHEMBL9166387 | 0.98 | KDM4E (1.00) | KDM4EMAPTMAPK1TAAR1ADRA2A | |
| Dopamine SCHEMBL8505 | 0.98 | KDM4E (1.00) | KDM4EMAPTMAPK1TAAR1ADRA2A | |
| Dopamine SCHEMBL29375089 | 0.98 | KDM4E (1.00) | KDM4EMAPTMAPK1TAAR1ADRA2A | |
| Dopamine SCHEMBL28317302 | 0.96 | KDM4E (0.92) | KDM4EMAPTMAPK1TAAR1ADRA2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 25 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20260121095-A1 | Advanced Ion Exchange Membranes And Applications Thereof | WILLIAMS RICHARD KENT (US) | 2026-04-30 | — | — | US | disclosed |
| WO-2025128460-A1 | ADVANCED ION EXCHANGE MEMBRANES AND APPLICATIONS THEREOF | WILLIAMS RICHARD KENT (US) | 2025-06-19 | — | — | WO | disclosed |
| US-12128290-B1 | Digital patch for discrete signaling, a baseball glove including same, and related method of manufacture | Lifeware Labs, LLC (US) | 2024-10-29 | — | — | US | disclosed |
| US-11673038-B1 | Digital patch for discrete signaling, a baseball glove including same, and related method of manufacture | Lifeware Labs, LLC (US) | 2023-06-13 | — | — | US | disclosed |
| CN-112472818-B | Nano material using modified natural melanin as carrier, and preparation method and application thereof | 安徽农业大学 | 2022-05-03 | — | — | CN | disclosed |
| US-11266897-B1 | Digital patch for discrete signaling, a baseball glove including same, and related method of manufacture | Lifeware Labs, LLC (US) | 2022-03-08 | — | — | US | disclosed |
| CN-112472818-A | Nano material using modified natural melanin as carrier, and preparation method and application thereof | 安徽农业大学 | 2021-03-12 | — | — | CN | disclosed |
| CN-111748120-A | Polydopamine-doped glucan hydrogel porous scaffold, and preparation method and application thereof | 温州医科大学 | 2020-10-09 | — | — | CN | disclosed |
| CN-110433316-A | A kind of photo-thermal/ion Synergistic antimicrobial hydrogel and its preparation method and application | SHANGHAI INST CERAMICS CAS | 2019-11-12 | — | — | CN | disclosed |
| CN-110130091-A | A kind of spinning milk protein fiber and preparation method thereof | 谭运桂 | 2019-08-16 | — | — | CN | disclosed |
| CN-106290520-A | A kind of preparation method of the electrochemical sensor with surface cure polypeptide probe | 微泰医疗器械(杭州)有限公司 | 2017-01-04 | — | — | CN | disclosed |
| US-9040580-B2 | Method for prevention or treatment of degenerative neurologial brain disorders | BRAINTROPIA CO., LTD. (KR) | 2015-05-26 | — | — | US | disclosed |
| CN-103079556-B | A pharmaceutical composition for preventing or treating neurodegenerative brain function disorder | BRAINTROPIA CO LTD | 2015-05-13 | — | — | CN | disclosed |
| US-20130178527-A1 | METHOD FOR PREVENTION OR TREATMENT OF DEGENERATIVE NEUROLOGIAL BRAIN DISORDERS | BRAINTROPIA CO., LTD. (KR) | 2013-07-11 | — | — | US | disclosed |
| EP-2612668-A2 | PHARMACEUTICAL COMPOSITION FOR THE PREVENTION OR TREATMENT OF DEGENERATIVE NEUROLOGICAL BRAIN DISORDERS | Braintropia Co. Ltd. (KR) | 2013-07-10 | — | — | EP | disclosed |
| CN-103079556-A | A pharmaceutical composition for preventing or treating neurodegenerative brain function disorder | BRAINTROPIA CO LTD | 2013-05-01 | — | — | CN | disclosed |
| US-20110105402-A1 | Silk Peptide For Improving Neuroprotective And Neurofunctional Effects And A Method Of Its Prepartion | BRAINGUARD CO., LTD. (KR) | 2011-05-05 | — | — | US | disclosed |
| EP-1773864-A4 | SILK PEPTIDE IMPROVING NEUROPROTECTIVE AND NEUROFUNCTIONAL EFFECTS AND A METHOD OF ITS PREPARATION | BIOGRAND CO LTD (KR) | 2009-02-18 | — | — | EP | disclosed |
| EP-1773864-A1 | SILK PEPTIDE IMPROVING NEUROPROTECTIVE AND NEUROFUNCTIONAL EFFECTS AND A METHOD OF ITS PREPARATION | Biogrand Co., Ltd. (KR) | 2007-04-18 | — | — | EP | disclosed |
| WO-2006014033-A1 | SILK PEPTIDE IMPROVING NEUROPROTECTIVE AND NEUROFUNCTIONAL EFFECTS AND A METHOD OF ITS PREPARATION | BRAINGUARD CO., LTD. (KR) | 2006-02-09 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20260121095-A1 | Advanced Ion Exchange Membranes And Applications Thereof | MYOC, MB, MYOF | KDM4E 3825/4885MAPT 3875/4885MAPK1 3053/4885 |
| US-20130178527-A1 | METHOD FOR PREVENTION OR TREATMENT OF DEGENERATIVE NEUROLOGIAL BRAIN DISORDERS | PSEN1, PSEN2, PYGB | KDM4E 3426/4885MAPT 32/4885MAPK1 3287/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.