SCHEMBL18740128

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

	Compound	similarity	top predicted	shared targets
	SCHEMBL18740275	0.90	LMNA (0.46)	CYP1A2CYP3A4CYP2C9CYP2C19MAPT
	SCHEMBL18758616	0.89	BRD4 (0.42)	CYP1A2CYP3A4CYP2C9CYP2C19MAPT
	SCHEMBL18740254	0.86	CYP1A2 (0.42)	CYP1A2CYP3A4CYP2C9CYP2C19MAPT
	SCHEMBL29894128	0.84	PTGER4 (0.47)	CYP1A2CYP3A4CYP2C9CYP2C19MAPT
	SCHEMBL28624098	0.84	PTGER4 (0.47)	CYP1A2CYP3A4CYP2C9CYP2C19MAPT
	SCHEMBL18758537	0.84	PTGER4 (0.47)	CYP1A2CYP3A4CYP2C9CYP2C19MAPT
	SCHEMBL18740013	0.83	CISD2 (0.39)	MAPTLMNACCR1ALDH1A1MAPK1
	SCHEMBL18740092	0.82	PKM (0.45)	CYP1A2CYP3A4CYP2C9CYP2C19MAPT
	SCHEMBL18758571	0.80	PKM (0.41)	CYP1A2CYP3A4CYP2C9CYP2C19MAPT
	SCHEMBL18758504	0.77	PTGER4 (0.51)	—

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 16 patents. claimed = in the patent's claims; disclosed = body only.

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (6 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.