SCHEMBL18758616

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

	Compound	similarity	top predicted	shared targets
	SCHEMBL18740013	0.90	CISD2 (0.39)	MAPTLMNACCR1POLBALDH1A1
	SCHEMBL18740128	0.89	CYP1A2 (0.44)	MAPTLMNATP53SMN1; SMN2CCR1
	SCHEMBL18758717	0.86	CCR1 (0.39)	BRD4BRD2BRD3MAPTLMNA
	SCHEMBL18740351	0.83	NOX4 (0.39)	MAPTLMNACCR1POLBCYP2C9
	SCHEMBL18758724	0.83	BRD4 (0.45)	BRD4BRD2BRD3MAPTSMN1; SMN2
	SCHEMBL28961686	0.83	BRD4 (0.45)	BRD4BRD2BRD3MAPTSMN1; SMN2
	SCHEMBL18740218	0.82	MEN1 (0.44)	MAPTLMNATP53SMN1; SMN2POLB
	SCHEMBL18740275	0.81	LMNA (0.46)	MAPTLMNATP53SMN1; SMN2POLB
	SCHEMBL18740296	0.78	MEN1 (0.39)	MAPTLMNATP53SMN1; SMN2POLB
	SCHEMBL18740243	0.77	PTGER4 (0.51)	BRD4BRD2BRD3CYP1A2CYP2C9

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 14 patents. claimed = in the patent's claims; disclosed = body only.

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (6 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.