SCHEMBL18740013

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

	Compound	similarity	top predicted	shared targets
	SCHEMBL18740351	0.93	NOX4 (0.39)	CISD2MEN1KMT2ACFTRNOX4
	SCHEMBL18758616	0.90	BRD4 (0.42)	ALDH1A1POLBGAAMAPTCCR1
	SCHEMBL18740275	0.87	LMNA (0.46)	MEN1KMT2AALDH1A1POLBGAA
	SCHEMBL18740127	0.85	NOTUM (0.39)	MEN1KMT2AMAPTHDAC1CCR1
	SCHEMBL18740128	0.83	CYP1A2 (0.44)	MEN1KMT2AALDH1A1GAAKDM4E
	SCHEMBL18758566	0.83	PTGER4 (0.42)	ALDH1A1
	SCHEMBL18739965	0.81	MEN1 (0.44)	MEN1KMT2AALDH1A1KDM4EHDAC1
	SCHEMBL18739970	0.79	NOX4 (0.37)	MEN1KMT2ANOX4ALDH1A1HDAC1
	SCHEMBL18758538	0.77	PDE2A (0.43)	ALDH1A1
	SCHEMBL18740168	0.77	KDM4E (0.41)	MEN1KMT2AALDH1A1POLBKDM4E

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 14 patents. claimed = in the patent's claims; disclosed = body only.

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (6 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.