Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TDO2 | P48775 | 4/20 | 0.40 |
| ▸ | KCNH2 | Q12809 | 2/20 | 0.39 |
| ▸ | PSEN1 | P49768 | 1/20 | 0.38 |
| ▸ | PSEN2 | P49810 | 1/20 | 0.38 |
| ▸ | APH1B | Q8WW43 | 1/20 | 0.38 |
| ▸ | NCSTN | Q92542 | 1/20 | 0.38 |
| ▸ | APH1A | Q96BI3 | 1/20 | 0.38 |
| ▸ | PSENEN | Q9NZ42 | 1/20 | 0.38 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.38 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.38 |
| ▸ | SLC1A3 | P43003 | 1/20 | 0.38 |
| ▸ | SLC1A2 | P43004 | 1/20 | 0.38 |
| ▸ | SLC1A1 | P43005 | 1/20 | 0.38 |
| ▸ | CA2 | P00918 | 2/20 | 0.37 |
| ▸ | CA1 | P00915 | 1/20 | 0.37 |
| ▸ | ALPL | P05186 | 1/20 | 0.37 |
| ▸ | MMP1 | P03956 | 1/20 | 0.37 |
| ▸ | MMP2 | P08253 | 1/20 | 0.37 |
| ▸ | MMP3 | P08254 | 1/20 | 0.37 |
| ▸ | MMP7 | P09237 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL19156557 | 0.94 | CA2 (0.40) | TDO2SMN1; SMN2ALDH1A1CA2CA1 | |
| SCHEMBL20820916 | 0.87 | CA12 (0.40) | SMN1; SMN2CA2CA12CA9MGAT2 | |
| SCHEMBL19156975 | 0.86 | MMP1 (0.46) | TDO2SMN1; SMN2ALDH1A1CA2MMP1 | |
| SCHEMBL18744734 | 0.86 | FEN1 (0.37) | CA2CA12CA9ALOX5APFEN1 | |
| SCHEMBL19517911 | 0.85 | KMT2A (0.41) | SMN1; SMN2SLC1A3SLC1A2SLC1A1CA2 | |
| SCHEMBL19853185 | 0.85 | TDO2 (0.41) | TDO2SMN1; SMN2MMP1MMP2MMP3 | |
| SCHEMBL19156928 | 0.83 | ALOX5AP (0.46) | TDO2SMN1; SMN2CA2MMP1MMP2 | |
| SCHEMBL19681317 | 0.83 | ALOX5AP (0.46) | TDO2SMN1; SMN2CA2MMP1MMP2 | |
| SCHEMBL23953182 | 0.82 | CA12 (0.39) | SMN1; SMN2CA2CA12CA9MGAT2 | |
| SCHEMBL19156546 | 0.82 | CA12 (0.39) | SMN1; SMN2CA2CA12CA9MGAT2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-10233147-B2 | N-(4-hydroxy-4-methyl-cyclohexyl)-4-phenyl-benzenesulfonamides and N-(4-hydroxy-4-methyl-cyclohexyl)-4-(2-pyridyl)benzenesulfonamides and their therapeutic use | PIMCO 2664 LIMITED (GB) | 2019-03-19 | — | — | US | disclosed |
| US-9624167-B2 | N-(4-hydroxy-4-methyl-cyclohexyl)-4-phenyl-benzenesulfonamides and N-(4-hydroxy-4-methyl-cyclohexyl)-4-(2-pyridyl)benzenesulfonamides and their therapeutic use | PIMCO 2664 LIMITED (GB) | 2017-04-18 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-10233147-B2 | N-(4-hydroxy-4-methyl-cyclohexyl)-4-phenyl-benzenesulfonamides and N-(4-hydroxy-4-methyl-cyclohexyl)-4-(2-pyridyl)benzenesulfonamides and their therapeutic use | BRCA1, TPMT, SOST | TDO2 3683/4885KCNH2 4081/4885PSEN1 1834/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.