Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.42 |
| ▸ | DRD4 | P21917 | 1/20 | 0.42 |
| ▸ | EGFR | P00533 | 6/20 | 0.40 |
| ▸ | ERBB2 | P04626 | 6/20 | 0.40 |
| ▸ | ERBB3 | P21860 | 1/20 | 0.39 |
| ▸ | KDR | P35968 | 1/20 | 0.39 |
| ▸ | PTK2 | Q05397 | 1/20 | 0.39 |
| ▸ | DRD2 | P14416 | 1/20 | 0.39 |
| ▸ | SLC6A4 | P31645 | 1/20 | 0.39 |
| ▸ | OPRM1 | P35372 | 1/20 | 0.38 |
| ▸ | OPRD1 | P41143 | 1/20 | 0.38 |
| ▸ | OPRK1 | P41145 | 1/20 | 0.38 |
| ▸ | OPRL1 | P41146 | 1/20 | 0.38 |
| ▸ | MEN1 | O00255 | 1/20 | 0.38 |
| ▸ | LMNA | P02545 | 1/20 | 0.38 |
| ▸ | HTR1E | P28566 | 1/20 | 0.38 |
| ▸ | HTT | P42858 | 1/20 | 0.38 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.38 |
| ▸ | S1PR3 | Q99500 | 1/20 | 0.38 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL18729770 | 0.84 | CHRNB2 (0.49) | KDM4EOPRM1OPRD1OPRK1OPRL1 | |
| SCHEMBL18751620 | 0.84 | CHRNB2 (0.49) | KDM4EOPRM1OPRD1OPRK1OPRL1 | |
| SCHEMBL17130333 | 0.84 | CHRNB2 (0.49) | KDM4EOPRM1OPRD1OPRK1OPRL1 | |
| SCHEMBL18751622 | 0.82 | CYP2D6 (0.41) | KDM4EOPRM1OPRD1OPRK1OPRL1 | |
| SCHEMBL17130329 | 0.82 | OPRM1 (0.44) | OPRM1OPRD1OPRK1OPRL1MEN1 | |
| SCHEMBL17114338 | 0.81 | CYP2D6 (0.40) | KDM4EOPRM1OPRD1OPRK1OPRL1 | |
| SCHEMBL17114337 | 0.81 | CYP2D6 (0.40) | KDM4EOPRM1OPRD1OPRK1OPRL1 | |
| SCHEMBL18768490 | 0.79 | KDM4E (0.39) | KDM4EOPRM1OPRD1OPRK1OPRL1 | |
| SCHEMBL17114334 | 0.78 | HSD11B1 (0.42) | KDM4EOPRD1CYP2D6 | |
| SCHEMBL17114339 | 0.78 | NR1H2 (0.48) | KDM4EOPRD1OPRK1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-9981957-B2 | Synthetic process | THE UNIVERSITY OF LIVERPOOL (GB) | 2018-05-29 | — | — | US | disclosed |
| US-9981957-B2 | Synthetic process | THE UNIVERSITY OF LIVERPOOL (GB) | 2018-05-29 | — | — | US | disclosed |
| US-20170107208-A1 | SYNTHETIC PROCESS | THE UNIVERSITY OF LIVERPOOL (GB) | 2017-04-20 | — | — | US | disclosed |
| US-20170107208-A1 | SYNTHETIC PROCESS | THE UNIVERSITY OF LIVERPOOL (GB) | 2017-04-20 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20170107208-A1 | SYNTHETIC PROCESS | PIR, SRM, SMS | KDM4E 1105/4885DRD4 17/4885EGFR 2132/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.