Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NOS2 | P35228 | 1/20 | 0.52 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.47 |
| ▸ | RAB9A | P51151 | 7/20 | 0.45 |
| ▸ | TSHR | P16473 | 2/20 | 0.45 |
| ▸ | NPC1 | O15118 | 6/20 | 0.44 |
| ▸ | SMN1; SMN2 | Q16637 | 4/20 | 0.44 |
| ▸ | TP53 | P04637 | 3/20 | 0.44 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.44 |
| ▸ | PKM | P14618 | 2/20 | 0.44 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.44 |
| ▸ | POLB | P06746 | 1/20 | 0.44 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.42 |
| ▸ | ADORA2A | P29274 | 1/20 | 0.42 |
| ▸ | LMNA | P02545 | 1/20 | 0.42 |
| ▸ | GAA | P10253 | 1/20 | 0.42 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.42 |
| ▸ | GALR3 | O60755 | 1/20 | 0.41 |
| ▸ | NR2F2 | P24468 | 1/20 | 0.41 |
| ▸ | PDE2A | O00408 | 2/20 | 0.41 |
| ▸ | PDE10A | Q9Y233 | 2/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL12648806 | 0.80 | MEN1 (0.57) | RAB9ATSHRNPC1SMN1; SMN2TP53 | |
| SCHEMBL13271318 | 0.79 | RAB9A (0.45) | RAB9ATSHRNPC1SMN1; SMN2TP53 | |
| SCHEMBL18753204 | 0.78 | PDE2A (0.47) | NOS2TDP1ADORA2APDE2APDE10A | |
| SCHEMBL13271457 | 0.76 | ALDH1A1 (0.57) | TDP1RAB9ATSHRNPC1SMN1; SMN2 | |
| SCHEMBL8010509 | 0.76 | RECQL (0.64) | RAB9ATSHRALDH1A1HTTMEN1 | |
| SCHEMBL29145186 | 0.76 | KMT2A (0.47) | RAB9ANPC1SMN1; SMN2KDM4EPKM | |
| SCHEMBL18872352 | 0.76 | KMT2A (0.61) | NOS2TDP1RAB9ATSHRNPC1 | |
| SCHEMBL21037530 | 0.76 | ALKBH5 (0.50) | NOS2TDP1RAB9ANPC1SMN1; SMN2 | |
| SCHEMBL5144258 | 0.75 | NOS2 (0.61) | NOS2TDP1RAB9ATSHRNPC1 | |
| SCHEMBL28604710 | 0.75 | RAB9A (0.41) | RAB9ATSHRNPC1SMN1; SMN2TP53 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2802594-B1 | METAL COMPLEXES WITH DIBENZO[F,H]QUINOXALINES | UDC IRELAND LTD (IE) | 2017-04-19 | — | — | EP | disclosed |
| EP-1966343-B1 | ELECTROLUMINESCENT METAL COMPLEXES WITH TRIAZOLES | UDC IRELAND LTD (IE) | 2017-04-19 | — | — | EP | disclosed |