Predicted protein targets (top 10)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PDE2A | O00408 | 10/20 | 0.47 |
| ▸ | PDE10A | Q9Y233 | 9/20 | 0.45 |
| ▸ | NOS2 | P35228 | 1/20 | 0.41 |
| ▸ | NOD1 | Q9Y239 | 1/20 | 0.40 |
| ▸ | NOTUM | Q6P988 | 1/20 | 0.39 |
| ▸ | GSR | P00390 | 1/20 | 0.38 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.38 |
| ▸ | KIF11 | P52732 | 1/20 | 0.38 |
| ▸ | ADORA2A | P29274 | 1/20 | 0.38 |
| ▸ | PDE7A | Q13946 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL18752767 | 0.78 | NOS2 (0.52) | PDE2APDE10ANOS2TDP1ADORA2A | |
| SCHEMBL9631719 | 0.73 | HTR2B (0.51) | PDE2APDE10ATDP1KIF11 | |
| SCHEMBL26026805 | 0.71 | PDE2A (0.39) | PDE2APDE10ATDP1ADORA2A | |
| SCHEMBL26575816 | 0.71 | GSR (0.44) | PDE2APDE10AGSRPDE7A | |
| SCHEMBL26375546 | 0.70 | KDM4E (0.45) | PDE2AGSRKIF11 | |
| SCHEMBL9632272 | 0.69 | USP2 (0.46) | PDE2APDE10A | |
| SCHEMBL14463551 | 0.69 | ALDH1A1 (0.61) | — | |
| SCHEMBL1663643 | 0.68 | NOS2 (0.55) | NOS2NOD1TDP1 | |
| SCHEMBL18025753 | 0.68 | KIF11 (0.52) | NOTUMKIF11 | |
| SCHEMBL16674462 | 0.68 | PDE2A (0.54) | PDE2APDE10APDE7A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2802594-B1 | METAL COMPLEXES WITH DIBENZO[F,H]QUINOXALINES | UDC IRELAND LTD (IE) | 2017-04-19 | — | — | EP | disclosed |