Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NOS2 | P35228 | 1/20 | 0.55 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.54 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.54 |
| ▸ | HPGD | P15428 | 1/20 | 0.54 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.50 |
| ▸ | CYP2C9 | P11712 | 3/20 | 0.48 |
| ▸ | CYP2C19 | P33261 | 3/20 | 0.48 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.48 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.48 |
| ▸ | TP53 | P04637 | 2/20 | 0.46 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.46 |
| ▸ | NPC1 | O15118 | 1/20 | 0.46 |
| ▸ | POLB | P06746 | 1/20 | 0.46 |
| ▸ | RAB9A | P51151 | 1/20 | 0.46 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.46 |
| ▸ | LMNA | P02545 | 2/20 | 0.46 |
| ▸ | TSHR | P16473 | 1/20 | 0.46 |
| ▸ | PIK3CB | P42338 | 1/20 | 0.46 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.44 |
| ▸ | MEN1 | O00255 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL19073863 | 0.81 | NOS2 (0.55) | NOS2ALDH1A1KDM4EHPGDMAPK1 | |
| SCHEMBL2958001 | 0.78 | ALDH1A1 (0.56) | ALDH1A1KDM4EHPGDMAPK1CYP2C9 | |
| SCHEMBL30034162 | 0.77 | SMN1; SMN2 (0.55) | ALDH1A1KDM4EHPGDMAPK1CYP2C9 | |
| SCHEMBL6019499 | 0.77 | ALDH1A1 (0.54) | ALDH1A1KDM4EHPGDMAPK1CYP2C9 | |
| SCHEMBL5851401 | 0.77 | SMN1; SMN2 (0.55) | ALDH1A1KDM4EHPGDMAPK1CYP2C9 | |
| SCHEMBL5851398 | 0.77 | ALDH1A1 (0.54) | ALDH1A1KDM4EHPGDMAPK1CYP2C9 | |
| SCHEMBL10457804 | 0.77 | ALDH1A1 (0.54) | ALDH1A1KDM4EHPGDMAPK1CYP2C9 | |
| SCHEMBL12937256 | 0.76 | MAPK1 (0.74) | ALDH1A1KDM4EHPGDMAPK1CYP2C9 | |
| SCHEMBL3715629 | 0.75 | KDM4E (0.58) | ALDH1A1KDM4EHPGDCYP2C9CYP2C19 | |
| SCHEMBL30388095 | 0.75 | KDM4E (0.58) | ALDH1A1KDM4EHPGDCYP2C9CYP2C19 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2488486-A1 | HEMATOPOIETIC GROWTH FACTOR MIMETIC SMALL MOLECULE COMPOUNDS AND THEIR USES | Ligand Pharmaceuticals Inc. (US) | 2012-08-22 | — | — | EP | disclosed |
| WO-2011046954-A1 | HEMATOPOIETIC GROWTH FACTOR MIMETIC SMALL MOLECULE COMPOUNDS AND THEIR USES | LIGAND PHARMACEUTICALS INC. (US) | 2011-04-21 | — | — | WO | disclosed |
| US-20060106262-A1 | Electrooptic chromophores with large optical birefringence for applications at high speed and short wavelengths | OPTIMER PHOTONICS, INC. | 2006-05-18 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20060106262-A1 | Electrooptic chromophores with large optical birefringence for applications at high speed and short wavelengths | EYA2, CRY2, EYA3 | NOS2 1734/4885ALDH1A1 1560/4885KDM4E 1086/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.