Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | EPHX1 | P07099 | 1/20 | 0.41 |
| ▸ | OPRM1 | P35372 | 1/20 | 0.41 |
| ▸ | DNM1 | Q05193 | 2/20 | 0.37 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.37 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.37 |
| ▸ | TSHR | P16473 | 1/20 | 0.37 |
| ▸ | ADH1B | P00325 | 1/20 | 0.36 |
| ▸ | ADH1C | P00326 | 1/20 | 0.36 |
| ▸ | ADH1A | P07327 | 1/20 | 0.36 |
| ▸ | ADH4 | P08319 | 1/20 | 0.36 |
| ▸ | ADH7 | P40394 | 1/20 | 0.36 |
| ▸ | TRPM8 | Q7Z2W7 | 1/20 | 0.34 |
| ▸ | SPHK1 | Q9NYA1 | 1/20 | 0.34 |
| ▸ | CA1 | P00915 | 1/20 | 0.34 |
| ▸ | ADRB2 | P07550 | 4/20 | 0.34 |
| ▸ | CNR1 | P21554 | 1/20 | 0.34 |
| ▸ | CNR2 | P34972 | 1/20 | 0.34 |
| ▸ | TP53 | P04637 | 1/20 | 0.33 |
| ▸ | LMNA | P02545 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5520888 | 0.81 | TSHR (0.40) | EPHX1ALDH1A1CYP3A4TSHRADH1B | |
| SCHEMBL5520885 | 0.81 | EPHX1 (0.35) | EPHX1ALDH1A1CYP3A4TSHRADRB2 | |
| SCHEMBL23847897 | 0.80 | CYP2D6 (0.35) | EPHX1TSHRADH1BADH1CADH1A | |
| SCHEMBL11814650 | 0.79 | OPRM1 (0.42) | EPHX1OPRM1DNM1ALDH1A1CYP3A4 | |
| SCHEMBL24379840 | 0.77 | ADH1B (0.50) | EPHX1OPRM1DNM1TSHRADH1B | |
| SCHEMBL17088072 | 0.76 | ADRB2 (0.49) | EPHX1OPRM1DNM1ALDH1A1CYP3A4 | |
| SCHEMBL24870689 | 0.76 | DNM1 (0.46) | EPHX1OPRM1DNM1TSHRADH1B | |
| SCHEMBL20798577 | 0.76 | DNM1 (0.40) | EPHX1OPRM1DNM1ALDH1A1CYP3A4 | |
| SCHEMBL9210833 | 0.76 | DNM1 (0.46) | EPHX1OPRM1DNM1ALDH1A1CYP3A4 | |
| SCHEMBL20016418 | 0.76 | ADRB2 (0.49) | EPHX1OPRM1DNM1ALDH1A1CYP3A4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3156410-A1 | POLYENE MACROLIDE DERIVATIVE | SHIONOGI & CO., LTD. (JP) | 2017-04-19 | — | — | EP | disclosed |