Predicted protein targets (top 2)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ADORA2A | P29274 | 1/20 | 0.30 |
| ▸ | ADORA2B | P29275 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Hydrochloric Acid SCHEMBL29014779 | 0.69 | PKM (0.41) | — | |
| SCHEMBL23872178 | 0.67 | PKM (0.41) | — | |
| SCHEMBL22951260 | 0.64 | ALOX15 (0.33) | — | |
| SCHEMBL21848996 | 0.64 | GRN (0.36) | ADORA2AADORA2B | |
| SCHEMBL12859150 | 0.64 | LMNA (0.39) | — | |
| SCHEMBL21720383 | 0.63 | CNR1 (0.34) | ADORA2AADORA2B | |
| SCHEMBL769183 | 0.63 | LMNA (0.41) | ADORA2AADORA2B | |
| SCHEMBL14043795 | 0.63 | ASAH1 (0.42) | ADORA2AADORA2B | |
| SCHEMBL13683165 | 0.62 | TGFBR1 (0.42) | — | |
| SCHEMBL10472243 | 0.62 | CNR1 (0.35) | ADORA2AADORA2B |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2376478-B1 | PYRIDYLOXYINDOLES INHIBITORS OF VEGF-R2 AND USE THEREOF FOR TREATMENT OF DISEASE | NOVARTIS AG (CH) | 2017-04-19 | — | — | EP | disclosed |