Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CA14 | Q9ULX7 | 1/20 | 0.50 |
| ▸ | TSHR | P16473 | 4/20 | 0.43 |
| ▸ | MEN1 | O00255 | 3/20 | 0.43 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.43 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.42 |
| ▸ | MAPT | P10636 | 1/20 | 0.42 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.42 |
| ▸ | GAA | P10253 | 1/20 | 0.41 |
| ▸ | RECQL | P46063 | 1/20 | 0.41 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.40 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.40 |
| ▸ | HPGD | P15428 | 1/20 | 0.40 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.39 |
| ▸ | BIRC2 | Q13490 | 1/20 | 0.38 |
| ▸ | LMNA | P02545 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL805648 | 1.00 | CA14 (0.50) | CA14TSHRMEN1KMT2ASMN1; SMN2 | |
| SCHEMBL1884920 | 1.00 | CA14 (0.50) | CA14TSHRMEN1KMT2ASMN1; SMN2 | |
| SCHEMBL20393857 | 0.91 | CA14 (0.43) | CA14TSHRMEN1KMT2ASMN1; SMN2 | |
| SCHEMBL21738188 | 0.91 | CA14 (0.43) | CA14TSHRMEN1KMT2ASMN1; SMN2 | |
| SCHEMBL13645819 | 0.91 | CA14 (0.43) | CA14TSHRMEN1KMT2ASMN1; SMN2 | |
| SCHEMBL7776379 | 0.91 | CA14 (0.43) | CA14TSHRMEN1KMT2ASMN1; SMN2 | |
| SCHEMBL11664935 | 0.81 | CA14 (0.52) | CA14TSHRMEN1KMT2ASMN1; SMN2 | |
| SCHEMBL30493714 | 0.81 | MEN1 (0.44) | CA14TSHRMEN1KMT2ASMN1; SMN2 | |
| SCHEMBL5808282 | 0.80 | TSHR (0.46) | CA14TSHRSMN1; SMN2MAPTGAA | |
| SCHEMBL21488518 | 0.80 | GAA (0.39) | CA14TSHRMEN1KMT2ASMN1; SMN2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 157 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-105693541-B | A kind of synthetic method of ethyldopa | 湖南湘易康制药有限公司 | 2017-12-22 | — | — | CN | claimed |
| CN-105693541-A | Synthetic method of methyldopa | 湖南湘易康制药有限公司 | 2016-06-22 | — | — | CN | claimed |
| WO-2006119283-A2 | ANTI-ODOR COMPOSITIONS AND THERAPEUTIC USE | YU RUEY J (US) | 2006-11-09 | — | — | WO | claimed |
| US-20060251597-A1 | ANTI-ODOR COMPOSITIONS AND THERAPEUTIC USE | YU RUEY J | 2006-11-09 | — | — | US | claimed |
| US-20230338324-A1 | METHOD FOR TREATING RHEUMATOID ARTHRITIS | THE WILLIAM M YARBROUGH FOUNDATION | 2023-10-26 | — | — | US | disclosed |
| WO-2023181844-A1 | VIRAL INFECTION INHIBITOR, VIRAL INFECTION INHIBITING MEMBER, AND VIRAL INFECTION INHIBITING PAINT | 積水化学工業株式会社 | 2023-09-28 | — | — | WO | disclosed |
| US-20210179553-A1 | HYDROPERSULFIDE PRECURSORS | NATIONAL SCIENCE FOUNDATION | 2021-06-17 | — | — | US | disclosed |
| US-10793670-B2 | Synthesis of tyrosine derived polyarylates | MEDTRONIC, INC. (US) | 2020-10-06 | — | — | US | disclosed |
| US-10660969-B2 | Eight-arm polyethylene glycol derivative, production method therefor, and modified bio-related substance thereof | XIAMEN SINOPEG BIOTECH CO., LTD. (CN) | 2020-05-26 | — | — | US | disclosed |
| WO-2020047359-A1 | HYDROPERSULFIDE PRECURSORS | THE JOHNS HOPKINS UNIVERSITY (US) | 2020-03-05 | — | — | WO | disclosed |
| US-10434182-B2 | Eight-arm polyethylene glycol derivative, production method therefor, and modified bio-related substance thereof | XIAMEN SINOPEG BIOTECH CO., LTD. (CN) | 2019-10-08 | — | — | US | disclosed |
| US-20180214561-A1 | EIGHT-ARM POLYETHYLENE GLYCOL DERIVATIVE, PRODUCTION METHOD THEREFOR, AND MODIFIEDBIO-RELATEDSUBSTANCETHEREOF | XIAMEN SINOPEG BIOTECH CO., LTD. (CN) | 2018-08-02 | — | — | US | disclosed |
| US-5371256-A | With rhodium and iridium | CIBA-GEIGY CORPORATION (US) | 1994-12-06 | — | — | US | disclosed |
| CN-1075967-A | Fungicidal silicon-containing compounds, method for the production thereof and their use in agrochemical and pharmaceutical applications | SANKYO CO (JP) | 1993-09-08 | — | — | CN | disclosed |
| EP-0498507-A1 | Process for the preparation of enantiomers of alpha-amino acid derivatives by asymmetric hydrogenation | DSM N.V. (NL) | 1992-08-12 | — | — | EP | disclosed |
| EP-0145265-B1 | ALPHA-AMINO ACIDS THROUGH CATALYTIC REACTION OF CO AND A HYDROXYL COMPOUND WITH ENAMIDES | THE STANDARD OIL COMPANY (US) | 1989-09-20 | — | — | EP | disclosed |
| US-4749786-A | α-amino acids through catalytic reaction of CO and a hydroxyl compound with enamides | THE STANDARD OIL COMPANY (US) | 1988-06-07 | — | — | US | disclosed |
| US-4710574-A | HYDROCARBOXYLATION OF UNSATURATED AMIDES | THE STANDARD OIL COMPANY (US) | 1987-12-01 | — | — | US | disclosed |
| EP-0145265-A2 | Alpha-amino acids through catalytic reaction of CO and a hydroxyl compound with enamides | THE STANDARD OIL COMPANY (US) | 1985-06-19 | — | — | EP | disclosed |
| US-RE29843-E | Substituted thiazoles and flavoring processes and products produced thereby | INTERNATIONAL FLAVORS & FRAGRANCES INC. (US) | 1978-11-21 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (5 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-10434182-B2 | Eight-arm polyethylene glycol derivative, production method therefor, and modified bio-related substance thereof | MRPL38, ALG8, MRPS18A | CA14 642/4885TSHR 2869/4885MEN1 1772/4885 |
| US-10660969-B2 | Eight-arm polyethylene glycol derivative, production method therefor, and modified bio-related substance thereof | MRPL38, ALG8, COG8 | CA14 923/4885TSHR 3054/4885MEN1 1107/4885 |
| US-20180214561-A1 | EIGHT-ARM POLYETHYLENE GLYCOL DERIVATIVE, PRODUCTION METHOD THEREFOR, AND MODIFIEDBIO-RELATEDSUBSTANCETHEREOF | MRPL38, CXCL8, ALG8 | CA14 715/4885TSHR 2426/4885MEN1 2488/4885 |
| US-20210179553-A1 | HYDROPERSULFIDE PRECURSORS | GPX4, SQOR, GPX1 | CA14 3202/4885TSHR 3021/4885MEN1 2876/4885 |
| US-20230338324-A1 | METHOD FOR TREATING RHEUMATOID ARTHRITIS | MIF, TNF, MMP12 | CA14 423/4885TSHR 1323/4885MEN1 1232/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.