Methylene Chloride

Methylene Chloride

SCHEMBL187626

CCN(CC)CC.ClCCl

nearest known ligand 0.36

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Predicted protein targets (top 8)

geneUniProtsupporting neighboursconfidence
ALDH1A1 P00352 2/20 0.36
CYP1A2 P05177 1/20 0.31
CYP2C9 P11712 1/20 0.31
HPGD P15428 1/20 0.31
MAPK1 P28482 1/20 0.31
HIF1A Q16665 1/20 0.31
HSD17B10 Q99714 1/20 0.31
HRH3 Q9Y5N1 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
Methylene Chloride SCHEMBL15348142 0.96 ALDH1A1 (0.33) ALDH1A1
Methylene Chloride SCHEMBL14696854 0.96 LMNA (0.35) ALDH1A1
Methylene Chloride SCHEMBL9555746 0.96 ALDH1A1 (0.33) ALDH1A1
Methylene Chloride SCHEMBL153756 0.92 CYP2C9 (0.33) ALDH1A1CYP1A2CYP2C9HPGDMAPK1
Cyclohexane SCHEMBL7124692 0.89 HRH3 (0.32) CYP1A2HSD17B10HRH3
Alcohol SCHEMBL946131 0.89 ALDH1A1 (0.43) ALDH1A1CYP1A2CYP2C9HPGDMAPK1
Methylene Chloride SCHEMBL28283777 0.89
Methylene Chloride SCHEMBL9305751 0.89 CYP2C9 (0.32) ALDH1A1CYP1A2CYP2C9HPGDMAPK1
1,2-Dichloroethane SCHEMBL9678531 0.87 TSHR (0.42) ALDH1A1CYP1A2HSD17B10
Chloromethane SCHEMBL6905936 0.86

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 671 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-114213257-B System and method for recycling interface catalyst 聊城鲁西聚碳酸酯有限公司 2023-08-01 CN claimed
CN-114656421-A Indoxacarb hapten, indoxacarb antigen, indoxacarb antibody, detection device, preparation method and application thereof 深圳市易瑞生物技术股份有限公司 2022-06-24 CN claimed
EP-3383844-B1 PROCESS FOR THE PREPARATION OF CARBOPROST AND ITS TROMETHAMINE SALT CHINOIN GYOGYSZER ES VEGYESZETI TERMEKEK GYARA RT (HU) 2020-06-03 EP claimed
CN-111171047-A Fused dihydro-4H-pyrazolo [5,1-C ] [1,4] oxazinyl compounds for the treatment of CNS disorders 赛诺维信制药公司 2020-05-19 CN claimed
CN-111040010-A Synthetic method of sofosbuvir intermediate 上海红蓝医药科技有限公司 2020-04-21 CN claimed
CN-110294764-A A kind of podophyllotoxin derivative and preparation method thereof of azo key connection 中国科学院兰州化学物理研究所 2019-10-01 CN claimed
CN-110128665-A The Amphipathilic block polymer near infrared fluorescent probe of azo-based reductase response and application 苏州大学 2019-08-16 CN claimed
CN-106166480-B Adsorbent material and its preparation method and application a kind of while that there is cation exchange and reverse phase reserve capability 浙江省中医药研究院 2019-06-25 CN claimed
CN-106892954-B The preparation process of shellfish cholic acid difficult to understand 广州隽沐生物科技有限公司 2019-04-30 CN claimed
CN-109180676-A Spiral shell [indolizine-pyrazoline] derivative and preparation method of 3,4,5- trimethoxy substitution structure containing pyridazinone 绍兴文理学院元培学院 2019-01-11 CN claimed
CN-101885830-B Synthesis method of waterborne polyurethane emulsion UNIV TONGJI 2012-01-25 CN claimed
CN-102311353-A Aldehyde group-containing poly-aryl ether ketone monomer capable of being subjected to post-functionalization, and synthetic method thereof XIANGFAN CLIMSUNG POLYMER MATERIAL CO LTD 2012-01-11 CN claimed
CN-101885830-A Synthesis method of waterborne polyurethane emulsion UNIV TONGJI 2010-11-17 CN claimed
CN-101143916-B Method for preparing three hetero arms asteroid polymer UNIV FUDAN 2010-11-17 CN claimed
CN-101870857-A Emulsion type water-base polyurethane adhesive for polyurethane conveying belt and synthetic method thereof UNIV TONGJI 2010-10-27 CN claimed
CN-101143916-A Method for preparing three hetero arms asteroid polymer UNIV FUDAN (CN) 2008-03-19 CN claimed
CN-101104654-A Polymer containing multiple functional groups at end of the same and preparation method thereof UNIV FUDAN (CN) 2008-01-16 CN claimed
US-6214235-B1 ADSORPTION GENERAL ELECTRIC COMPANY 2001-04-10 US claimed
CN-1046167-A The method for preparing the brassinosteroid analogs intermediate UNIV YUNNAN (CN) 1990-10-17 CN claimed
CN-1037710-A The method of synthetic oil analogue of rape lactone UNIV YUNNAN (CN) 1989-12-06 CN claimed