Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CYP2C9 | P11712 | 2/20 | 0.33 |
| ▸ | HPGD | P15428 | 2/20 | 0.33 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.33 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.33 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.33 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.33 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.32 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.32 |
| ▸ | MEN1 | O00255 | 1/20 | 0.32 |
| ▸ | POLB | P06746 | 1/20 | 0.32 |
| ▸ | MAPT | P10636 | 1/20 | 0.32 |
| ▸ | THRB | P10828 | 1/20 | 0.32 |
| ▸ | APEX1 | P27695 | 1/20 | 0.32 |
| ▸ | HTT | P42858 | 1/20 | 0.32 |
| ▸ | RECQL | P46063 | 1/20 | 0.32 |
| ▸ | CACNA1B | Q00975 | 1/20 | 0.32 |
| ▸ | APBA1 | Q02410 | 1/20 | 0.32 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.32 |
| ▸ | MCL1 | Q07820 | 1/20 | 0.32 |
| ▸ | HKDC1 | Q2TB90 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Methylene Chloride SCHEMBL9305751 | 0.96 | CYP2C9 (0.32) | CYP2C9HPGDMAPK1HSD17B10CYP1A2 | |
| Methylene Chloride SCHEMBL187626 | 0.92 | ALDH1A1 (0.36) | CYP2C9HPGDMAPK1HSD17B10CYP1A2 | |
| Alcohol SCHEMBL946131 | 0.89 | ALDH1A1 (0.43) | CYP2C9HPGDMAPK1HSD17B10CYP1A2 | |
| Methylene Chloride SCHEMBL9555746 | 0.88 | ALDH1A1 (0.33) | ALDH1A1 | |
| Methylene Chloride SCHEMBL15348142 | 0.88 | ALDH1A1 (0.33) | ALDH1A1 | |
| Methylene Chloride SCHEMBL14696854 | 0.88 | LMNA (0.35) | ALDH1A1MAPTHTT | |
| Chloromethane SCHEMBL375766 | 0.88 | CYP2C9 (0.35) | CYP2C9HPGDMAPK1HSD17B10CYP1A2 | |
| Methyl Alcohol SCHEMBL341831 | 0.88 | — | — | |
| Acetic Acid SCHEMBL9639930 | 0.85 | FFAR3 (0.39) | ALDH1A1KDM4EMAPTTDP1 | |
| Acetonitrile SCHEMBL5210744 | 0.85 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 815 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-108484624-B | Irinotecan hydrochloride impurity and synthesis method and application thereof | 扬子江药业集团有限公司 | 2020-06-26 | — | — | CN | claimed |
| CN-109400538-A | The preparation method of penoxsuam raw medicine related impurities bis-CHYMP | 江苏中谱检测有限公司 | 2019-03-01 | — | — | CN | claimed |
| CN-102718827-B | Method for separating and purifying ginsenoside Rb3 | UNIV DALIAN | 2014-07-16 | — | — | CN | claimed |
| CN-102718827-A | Method for separating and purifying ginsenoside Rb3 | UNIV DALIAN | 2012-10-10 | — | — | CN | claimed |
| US-20240166658-A1 | PORPHYRIN DERIVATIVES AND USES THEREOF | UNIVERSITY OF TASMANIA (AU) | 2024-05-23 | — | — | US | disclosed |
| US-20240109893-A1 | PREPARATION AND APPLICATION METHOD OF HETEROCYCLIC COMPOUNDS AS KRAS INHIBITOR | SHANGHAI KECHOW PHARMA, INC. (CN) | 2024-04-04 | — | — | US | disclosed |
| US-20240083899-A1 | PURINONE DERIVATIVE | ONO PHARMACEUTICAL CO., LTD. (JP) | 2024-03-14 | — | — | US | disclosed |
| US-20240034748-A1 | Synthesis of Protected 3'-amino Nucleoside Monomers | GERON CORP (US) | 2024-02-01 | — | — | US | disclosed |
| CN-113717240-B | Nucleoside compound and preparation method thereof | 哈尔滨商业大学 | 2023-10-17 | — | — | CN | disclosed |
| WO-2023155826-A1 | MULTI-SUBSTITUTED TRICYCLIC FUSED HETEROCYCLIC COMPOUND, PHARMACEUTICAL COMPOSITION THEREOF AND USE THEREOF | 暨南大学 | 2023-08-24 | — | — | WO | disclosed |
| US-11717580-B2 | Cyclodextrin-linked polyvalent ligands for complexation of metal ions | UTI LP (CA) | 2023-08-08 | — | — | US | disclosed |
| WO-2023109929-A1 | HETEROCYCLIC COMPOUND HAVING ANTI-TUMOR ACTIVITY AND USE THEREOF | 石药集团中奇制药技术（石家庄）有限公司 | 2023-06-22 | — | — | WO | disclosed |
| US-4526988-A | Hydrolyzing alkyl 3-dioxolanyl-2,2-difluoro-3-hydroxy propionate | ELI LILLY AND COMPANY (US) | 1985-07-02 | — | — | US | disclosed |
| EP-0145434-A2 | Novel dihydropyridine derivatives and process for preparing the same | OTSUKA PHARMACEUTICAL CO., LTD. (JP) | 1985-06-19 | — | — | EP | disclosed |
| US-4476301-A | Oligonucleotides, a process for preparing the same and their application as mediators of the action of interferon | CENTRE NATIONAL DE LA RECHERCHE SCIENTIFIQUE (FR) | 1984-10-09 | — | — | US | disclosed |
| EP-0103381-A1 | Substituted anthra(1,9-cd)pyrazol-6(2H)-ones | WARNER-LAMBERT COMPANY (US) | 1984-03-21 | — | — | EP | disclosed |
| US-4438128-A | ADRENERGIC BLOCKERS | BOEHRINGER MANNHEIM GMBH (DE) | 1984-03-20 | — | — | US | disclosed |
| US-4171244-A | Enzyme-bound-polyidothyronine | SYVA COMPANY (US) | 1979-10-16 | — | — | US | disclosed |
| US-4154852-A | ANTIDEPRESSANTS | ROUSSEL UCLAF (FR) | 1979-05-15 | — | — | US | disclosed |
| US-4091115-A | ANTIDEPRESSANTS | ROUSSEL UCLAF (FR) | 1978-05-23 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (5 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20240034748-A1 | Synthesis of Protected 3'-amino Nucleoside Monomers | NT5C3B, RNMT, UMPS | CYP2C9 3196/4885HPGD 1724/4885MAPK1 2358/4885 |
| US-20240166658-A1 | PORPHYRIN DERIVATIVES AND USES THEREOF | PFAS, PCBP1, FGR | CYP2C9 626/4885HPGD 2952/4885MAPK1 4681/4885 |
| US-20240109893-A1 | PREPARATION AND APPLICATION METHOD OF HETEROCYCLIC COMPOUNDS AS KRAS INHIBITOR | KRAS, NRAS, HRAS | CYP2C9 1314/4885HPGD 701/4885MAPK1 52/4885 |
| US-11717580-B2 | Cyclodextrin-linked polyvalent ligands for complexation of metal ions | SLC39A14, PICALM, CDV3 | CYP2C9 3536/4885HPGD 3282/4885MAPK1 4516/4885 |
| US-20240083899-A1 | PURINONE DERIVATIVE | BTK, KIT, SYK | CYP2C9 190/4885HPGD 1040/4885MAPK1 493/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.