Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HRH3 | Q9Y5N1 | 1/20 | 0.32 |
| ▸ | LMNA | P02545 | 1/20 | 0.32 |
| ▸ | SLC6A2 | P23975 | 1/20 | 0.31 |
| ▸ | SLC6A4 | P31645 | 1/20 | 0.31 |
| ▸ | SLC6A3 | Q01959 | 1/20 | 0.31 |
| ▸ | MAPT | P10636 | 2/20 | 0.30 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.30 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.30 |
| ▸ | TSHR | P16473 | 1/20 | 0.30 |
| ▸ | NFKB1 | P19838 | 1/20 | 0.30 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.30 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Cyclohexane SCHEMBL8471239 | 0.89 | ADH1C (0.32) | HRH3 | |
| Methylene Chloride SCHEMBL187626 | 0.89 | ALDH1A1 (0.36) | HRH3CYP1A2HSD17B10 | |
| Methylene Chloride SCHEMBL14696854 | 0.85 | LMNA (0.35) | LMNAMAPTTSHR | |
| Fluoride SCHEMBL6463523 | 0.85 | ADH1C (0.31) | HRH3 | |
| Methylene Chloride SCHEMBL15348142 | 0.85 | ALDH1A1 (0.33) | — | |
| Methylene Chloride SCHEMBL9555746 | 0.85 | ALDH1A1 (0.33) | — | |
| Cyclohexane SCHEMBL10673286 | 0.83 | HRH3 (0.31) | HRH3 | |
| Methylene Chloride SCHEMBL153756 | 0.81 | CYP2C9 (0.33) | MAPTCYP1A2HSD17B10 | |
| Cyclopropane SCHEMBL28029468 | 0.81 | — | — | |
| Hydrochloric Acid SCHEMBL28029784 | 0.81 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20030105343-A1 | Benzofuran compounds | SHARP KABUSHIKI KAISHA (JP) | 2003-06-05 | — | — | US | disclosed |
| US-4853408-A | 4-phenylpropyl-indoles having antiarythmic activity | ROUSSEL UCLAF (FR) | 1989-08-01 | — | — | US | disclosed |
| US-4808609-A | Amino-(hydroxy)alkoxy-4-phenylpropyl indoles having antiarrythmic activity | ROUSSEL UCLAF (FR) | 1989-02-28 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20030105343-A1 | Benzofuran compounds | BBOX1, DDO, OGFOD1 | HRH3 3960/4885LMNA 859/4885SLC6A2 4450/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.