Predicted protein targets (top 4)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | OPRM1 | P35372 | 1/20 | 0.30 |
| ▸ | OPRD1 | P41143 | 1/20 | 0.30 |
| ▸ | OPRK1 | P41145 | 1/20 | 0.30 |
| ▸ | OPRL1 | P41146 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL18650812 | 0.78 | LMNA (0.30) | — | |
| SCHEMBL29348245 | 0.76 | OPRM1 (0.30) | OPRM1OPRD1OPRK1OPRL1 | |
| SCHEMBL23325924 | 0.74 | CYP2D6 (0.35) | OPRM1OPRD1OPRK1OPRL1 | |
| SCHEMBL23324152 | 0.68 | OPRM1 (0.32) | OPRM1OPRD1OPRK1OPRL1 | |
| SCHEMBL13216615 | 0.68 | RARA (0.35) | OPRM1OPRD1OPRK1OPRL1 | |
| SCHEMBL22511149 | 0.67 | SIGMAR1 (0.36) | — | |
| SCHEMBL25041233 | 0.67 | SMN1; SMN2 (0.36) | — | |
| SCHEMBL1106523 | 0.66 | — | — | |
| SCHEMBL13431755 | 0.65 | PRMT1 (0.37) | OPRM1OPRD1OPRK1OPRL1 | |
| SCHEMBL18650801 | 0.65 | PER2 (0.34) | OPRM1OPRD1OPRK1OPRL1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3365338-A1 | SUBSTITUTED MORPHOLINE DERIVATIVES HAVING ACTIVITY AGAINST PAIN | Laboratorios Del. Dr. Esteve, S.A. (ES) | 2018-08-29 | — | — | EP | disclosed |
| WO-2017067665-A1 | SUBSTITUTED MORPHOLINE DERIVATIVES HAVING ACTIVITY AGAINST PAIN | LABORATORIOS DEL DR. ESTEVE, S.A. (ES) | 2017-04-27 | — | — | WO | disclosed |