Known targets — ChEMBL curated mechanism
GABRA1GABRA2GABRA3GABRA4GABRA5GABRA6GABRB1GABRB2GABRB3GABRDGABREGABRG1GABRG2GABRG3GABRPGABRQ
The experimentally established mechanism targets of Water. The predicted profile below is derived independently by chemical similarity — agreement is a validation signal, a miss is honest.
Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | DNM1 | Q05193 | 2/20 | 0.56 |
| ▸ | MEN1 | O00255 | 2/20 | 0.55 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.55 |
| ▸ | TP53 | P04637 | 2/20 | 0.55 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.55 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.55 |
| ▸ | HTT | P42858 | 2/20 | 0.53 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.47 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.45 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.45 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.45 |
| ▸ | SLC22A1 | O15245 | 1/20 | 0.44 |
| ▸ | CNR2 | P34972 | 2/20 | 0.41 |
| ▸ | BCHE | P06276 | 1/20 | 0.40 |
| ▸ | ACHE | P22303 | 1/20 | 0.40 |
| ▸ | SIGMAR1 | Q99720 | 1/20 | 0.40 |
| ▸ | CHRNB4 | P30926 | 1/20 | 0.40 |
| ▸ | CHRNA3 | P32297 | 1/20 | 0.40 |
| ▸ | CHRNA7 | P36544 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL81000 | 0.98 | DNM1 (0.58) | DNM1MEN1KMT2ATP53SMN1; SMN2 | |
| Hydrogen Sulfide SCHEMBL5998244 | 0.98 | DNM1 (0.58) | DNM1MEN1KMT2ATP53SMN1; SMN2 | |
| Bromide SCHEMBL29110289 | 0.96 | DNM1 (0.59) | DNM1MEN1KMT2ATP53SMN1; SMN2 | |
| Fluoride Ion SCHEMBL636828 | 0.96 | DNM1 (0.56) | DNM1MEN1KMT2ATP53SMN1; SMN2 | |
| Bromide SCHEMBL29110287 | 0.96 | DNM1 (0.56) | DNM1MEN1KMT2ATP53SMN1; SMN2 | |
| Hydrogen Sulfide SCHEMBL5998240 | 0.96 | DNM1 (0.56) | DNM1MEN1KMT2ATP53SMN1; SMN2 | |
| Bromide SCHEMBL240143 | 0.96 | DNM1 (0.59) | DNM1MEN1KMT2ATP53SMN1; SMN2 | |
| Iodide SCHEMBL239944 | 0.96 | DNM1 (0.56) | DNM1MEN1KMT2ATP53SMN1; SMN2 | |
| Bromide SCHEMBL28701241 | 0.96 | DNM1 (0.56) | DNM1MEN1KMT2ATP53SMN1; SMN2 | |
| Hydrochloric Acid SCHEMBL194044 | 0.96 | MEN1 (0.59) | DNM1MEN1KMT2ATP53SMN1; SMN2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 771 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-12448568-B2 | Etching compositions | FUJIFILM ELECTRONIC MATERIALS U.S.A., INC. (US) | 2025-10-21 | — | — | US | claimed |
| CN-120058450-A | C (sp) in benzene ring2) Method for deuteration of the H bond | 云南大学 | 2025-05-30 | — | — | CN | claimed |
| EP-4551989-A1 | CLEANING COMPOSITIONS | FUJIFILM ELECTRONIC MATERIALS U.S.A., INC. (US) | 2025-05-14 | — | — | EP | claimed |
| CN-119976882-A | Method for synthesizing hierarchical pore molecular sieve | 中国石油大学(华东) | 2025-05-13 | — | — | CN | claimed |
| EP-4490772-A2 | ETCHING COMPOSITIONS | FUJIFILM Electronic Materials U.S.A, Inc. (US) | 2025-01-15 | — | — | EP | claimed |
| CN-119219550-A | Reduction method of carboxylic ester compound | 云南大学 | 2024-12-31 | — | — | CN | claimed |
| CN-116589921-B | Silicon-rich anti-reflection coating resin material and preparation method thereof | 宁波杭州湾新材料研究院 | 2024-12-03 | — | — | CN | claimed |
| CN-119013768-A | Etching composition | 富士胶片电子材料美国有限公司 | 2024-11-22 | — | — | CN | claimed |
| CN-118652735-A | Low-corrosion chip photoresist cleaning solution and preparation method and application thereof | 江苏奥首材料科技有限公司 | 2024-09-17 | — | — | CN | claimed |
| CN-118126783-A | Tungsten process cleaning agent for removing residues after dry etching by one-step method | 深圳迪道微电子科技有限公司 | 2024-06-04 | — | — | CN | claimed |
| WO-2012051380-A2 | COMPOSITION FOR AND METHOD OF SUPPRESSING TITANIUM NITRIDE CORROSION | ADVANCED TECHNOLOGY MATERIALS, INC. (US) | 2012-04-19 | — | — | WO | claimed |
| CN-102134249-A | Preparation method of chiral 5-protection-2-thia-5-aza-bicyclic (2.2.1) hepta-3-ketone | TIANJIN JINGYE FINE CHEMICALS CO LTD | 2011-07-27 | — | — | CN | claimed |
| US-20080293831-A1 | Method for producing zirconia sol | NISSAN CHEMICAL INDUSTRIES, LTD. (JP) | 2008-11-27 | — | — | US | claimed |
| EP-1994979-A1 | Method for producing zirconia sol | Nissan Chemical Industries, Ltd. (JP) | 2008-11-26 | — | — | EP | claimed |
| CN-101311121-A | Preparation of zirconia sol | NISSAN CHEMICAL IND LTD (JP) | 2008-11-26 | — | — | CN | claimed |
| CN-1505479-A | Pesticide composition containing oxalic acid | ������ɽ���� | 2004-06-16 | — | — | CN | claimed |
| EP-1389912-A2 | PESTICIDE COMPOSITIONS CONTAINING OXALIC ACID | Monsanto Technology LLC (US) | 2004-02-25 | — | — | EP | claimed |
| WO-2002069718-A2 | PESTICIDE COMPOSITIONS CONTAINING OXALIC ACID | MONSANTO TECHNOLOGY LLC (US) | 2002-09-12 | — | — | WO | claimed |
| US-20020123430-A1 | Pesticide compositions containing oxalic acid | MONSANTO TECHNOLOGY LLC | 2002-09-05 | — | — | US | claimed |
| US-4530830-A | Mixture containing emulsifier | REVLON, INC. (US) | 1985-07-23 | — | — | US | claimed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20020123430-A1 | Pesticide compositions containing oxalic acid | OTC, SLC47A1, SLC47A2 | DNM1 1867/4885MEN1 3332/4885KMT2A 4494/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.