Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ACACB | O00763 | 5/20 | 0.47 |
| ▸ | DRD2 | P14416 | 3/20 | 0.46 |
| ▸ | TGFBR1 | P36897 | 1/20 | 0.45 |
| ▸ | MEN1 | O00255 | 3/20 | 0.44 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.44 |
| ▸ | CKS1B | P61024 | 1/20 | 0.44 |
| ▸ | SKP1 | P63208 | 1/20 | 0.44 |
| ▸ | SKP2 | Q13309 | 1/20 | 0.44 |
| ▸ | CACNA1B | Q00975 | 1/20 | 0.44 |
| ▸ | ACACA | Q13085 | 4/20 | 0.43 |
| ▸ | PKM | P14618 | 2/20 | 0.42 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.42 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.42 |
| ▸ | DRD4 | P21917 | 1/20 | 0.42 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.41 |
| ▸ | POLB | P06746 | 1/20 | 0.41 |
| ▸ | MAPT | P10636 | 1/20 | 0.41 |
| ▸ | MCL1 | Q07820 | 1/20 | 0.41 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL18766914 | 0.87 | EEF2K (0.46) | ACACBDRD2CKS1BSKP1SKP2 | |
| SCHEMBL18767431 | 0.86 | MEN1 (0.46) | DRD2MEN1KMT2APKMSMN1; SMN2 | |
| SCHEMBL29725632 | 0.86 | MEN1 (0.57) | DRD2MEN1KMT2AKDM4EDRD4 | |
| SCHEMBL18766905 | 0.84 | KMT2A (0.54) | ACACBDRD2TGFBR1MEN1KMT2A | |
| SCHEMBL18766901 | 0.82 | MAPT (0.46) | ACACBDRD2TGFBR1MEN1KMT2A | |
| SCHEMBL18768209 | 0.81 | ADRA1D (0.41) | MEN1KMT2AALDH1A1 | |
| SCHEMBL18767433 | 0.78 | HTR1A (0.46) | — | |
| SCHEMBL32665269 | 0.75 | CKS1B (0.55) | ACACBDRD2KMT2ACKS1BSKP1 | |
| SCHEMBL29725623 | 0.75 | ACHE (0.61) | DRD2MEN1KMT2ASMN1; SMN2DRD4 | |
| SCHEMBL23559679 | 0.74 | CKS1B (0.48) | ACACBDRD2MEN1KMT2ACKS1B |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2017066705-A1 | COMPOUNDS, COMPOSITIONS AND METHODS OF USE AGAINST STRESS GRANULES | AQUINNAH PHARMACEUTICALS, INC. (US) | 2017-04-20 | — | — | WO | disclosed |