Predicted protein targets (top 10)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ADRA1D | P25100 | 1/20 | 0.41 |
| ▸ | ADRA1A | P35348 | 1/20 | 0.41 |
| ▸ | ADRA1B | P35368 | 1/20 | 0.41 |
| ▸ | HTR1A | P08908 | 1/20 | 0.41 |
| ▸ | SLC6A4 | P31645 | 1/20 | 0.41 |
| ▸ | CASR | P41180 | 1/20 | 0.41 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.40 |
| ▸ | MEN1 | O00255 | 1/20 | 0.40 |
| ▸ | UTS2R | Q9UKP6 | 1/20 | 0.39 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL18768166 | 0.86 | MAOA (0.39) | CASRKMT2A | |
| SCHEMBL18767431 | 0.85 | MEN1 (0.46) | KMT2AMEN1ALDH1A1 | |
| SCHEMBL18767433 | 0.81 | HTR1A (0.46) | HTR1ASLC6A4 | |
| SCHEMBL18768210 | 0.81 | ACACB (0.47) | KMT2AMEN1ALDH1A1 | |
| SCHEMBL18766912 | 0.74 | MAOA (0.40) | CASRKMT2A | |
| SCHEMBL18768208 | 0.71 | MEN1 (0.43) | KMT2AMEN1 | |
| SCHEMBL18767434 | 0.71 | OPRD1 (0.45) | — | |
| SCHEMBL22827424 | 0.69 | TAAR1 (0.55) | ALDH1A1 | |
| SCHEMBL1965727 | 0.68 | CHRM2 (0.60) | ADRA1DADRA1AADRA1BKMT2AMEN1 | |
| SCHEMBL18766905 | 0.66 | KMT2A (0.54) | KMT2AMEN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2017066705-A1 | COMPOUNDS, COMPOSITIONS AND METHODS OF USE AGAINST STRESS GRANULES | AQUINNAH PHARMACEUTICALS, INC. (US) | 2017-04-20 | — | — | WO | disclosed |