Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | DRD2 | P14416 | 3/20 | 1.00 |
| ▸ | MAPKAPK2 | P49137 | 1/20 | 0.49 |
| ▸ | CCR3 | P51677 | 2/20 | 0.47 |
| ▸ | OPRL1 | P41146 | 6/20 | 0.46 |
| ▸ | OPRM1 | P35372 | 6/20 | 0.46 |
| ▸ | OPRD1 | P41143 | 2/20 | 0.46 |
| ▸ | OPRK1 | P41145 | 2/20 | 0.46 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.45 |
| ▸ | SLC18A3 | Q16572 | 1/20 | 0.45 |
| ▸ | AKT1 | P31749 | 1/20 | 0.44 |
| ▸ | AKT2 | P31751 | 1/20 | 0.44 |
| ▸ | AKT3 | Q9Y243 | 1/20 | 0.44 |
| ▸ | MEN1 | O00255 | 2/20 | 0.43 |
| ▸ | ADRA1A | P35348 | 2/20 | 0.41 |
| ▸ | NPC1 | O15118 | 1/20 | 0.40 |
| ▸ | LMNA | P02545 | 1/20 | 0.40 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.40 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.40 |
| ▸ | HTR1A | P08908 | 1/20 | 0.40 |
| ▸ | CHRM5 | P08912 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Hydrochloric Acid SCHEMBL11625365 | 0.98 | DRD2 (0.96) | DRD2MAPKAPK2CCR3OPRL1OPRM1 | |
| Hydrochloric Acid SCHEMBL2790980 | 0.96 | DRD2 (0.92) | DRD2MAPKAPK2CCR3OPRL1OPRM1 | |
| SCHEMBL654604 | 0.93 | DRD2 (0.86) | DRD2MAPKAPK2CCR3OPRL1OPRM1 | |
| SCHEMBL653842 | 0.88 | DRD2 (0.79) | DRD2MAPKAPK2CCR3OPRL1OPRM1 | |
| Hydrochloric Acid SCHEMBL29087281 | 0.86 | DRD2 (0.76) | DRD2MAPKAPK2CCR3OPRL1OPRM1 | |
| SCHEMBL29090112 | 0.84 | DRD2 (0.72) | DRD2CCR3OPRL1OPRM1OPRD1 | |
| SCHEMBL22022197 | 0.83 | DRD2 (0.70) | DRD2CCR3OPRL1OPRM1OPRD1 | |
| SCHEMBL652586 | 0.81 | DRD2 (0.68) | DRD2MAPKAPK2OPRM1OPRD1KMT2A | |
| Hydrochloric Acid SCHEMBL6504476 | 0.81 | DRD2 (0.68) | DRD2CCR3OPRL1OPRM1OPRD1 | |
| SCHEMBL16249345 | 0.80 | DRD2 (0.67) | DRD2CCR3OPRL1OPRM1OPRD1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 954 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-118297326-A | Multi-time scale optimal scheduling method and device for comprehensive energy system of transformer substation | 山东智源电力设计咨询有限公司 | 2024-07-05 | — | — | CN | claimed |
| CN-118125969-A | Haloperidol with excellent biological performance and preparation method and application thereof | 湖南洞庭药业股份有限公司 | 2024-06-04 | — | — | CN | claimed |
| CN-116143686-A | Preparation method of haloperidol impurity D | 深圳市江川医药技术有限公司 | 2023-05-23 | — | — | CN | claimed |
| CN-113122050-A | Quantum dot ink and preparation method of quantum dot film | TCL集团股份有限公司 | 2021-07-16 | — | — | CN | claimed |
| CN-112538042-A | Preparation method of haloperidol | 湖南洞庭药业股份有限公司 | 2021-03-23 | — | — | CN | claimed |
| US-10253006-B2 | Assay for the detection of the phenylpiperazine family | RANDOX LABORATORIES LIMITED (GB) | 2019-04-09 | — | — | US | claimed |
| US-20160229824-A1 | ASSAY FOR THE DETECTION OF THE PHENYLPIPERAZINE FAMILY | NORTHERN BANK LIMITED (IE) | 2016-08-11 | — | — | US | claimed |
| CN-102797043-B | Medicinal molecular fragment library and construction process thereof | Tianli (Tianjin) Technology Co., Ltd. (CN) | 2015-11-25 | — | — | CN | claimed |
| EP-2504324-B1 | SULTAM DERIVATIVES | HOFFMANN LA ROCHE (CH) | 2015-02-25 | — | — | EP | claimed |
| CN-102797043-A | Medicinal molecular fragment library and construction method thereof | CBB NETWORK CO LTD | 2012-11-28 | — | — | CN | claimed |
| WO-2004113391-A2 | IMPROVED PHARMACEUTICAL DRUG CANDIDATES AND METHODS FOR PREPARATION THEREOF | NEUROCHEM (INTERNATIONAL) LIMITED (CH) | 2004-12-29 | — | — | WO | claimed |
| US-20040072876-A1 | Substituted thiazole derivatives bearing 3-pyridyl groups, process for preparing the same and use thereof | TAKEDA PHARMACEUTICAL COMPANY LIMITED (JP) | 2004-04-15 | — | — | US | claimed |
| EP-1348706-A1 | SUBSTITUTED THIAZOLE DERIVATIVES BEARING 3-PYRIDYL GROUPS, PROCESS FOR PREPARING THE SAME AND USE THEREOF | Takeda Chemical Industries, Ltd. (JP) | 2003-10-01 | — | — | EP | claimed |
| EP-1077973-A2 | BENZOFURAN DERIVATIVES, PHARMACEUTICAL COMPOSITION CONTAINING THE SAME, AND A PROCESS FOR THE PREPARATION OF THE ACTIVE INGREDIENT | EGIS GYOGYSZERGYAR RT. (HU) | 2001-02-28 | — | — | EP | claimed |
| WO-2001005401-A1 | MELANOCORTIN RECEPTOR-3 LIGANDS TO TREAT SEXUAL DYSFUNCTION | TREGA BIOSCIENCES, INC. (US) | 2001-01-25 | — | — | WO | claimed |
| WO-1999058527-A2 | BENZOFURAN DERIVATIVES, PHARMACEUTICAL COMPOSITION CONTAINING THE SAME, AND A PROCESS FOR THE PREPARATION OF THE ACTIVE INGREDIENT | EGIS Gyógyszergyár Rt. (HU) | 1999-11-18 | — | — | WO | claimed |
| US-4284638-A | Pharmaceutical compositions with central depressant and antipsychotic activity having a butyrophenone derivative which is substituted in the 4-position and a C-(2-benzofuranyl)-piperidine or C-(2-benzofuranyl)-tetrahydro-pyridine | CIBA-GEIGY CORPORATION (US) | 1981-08-18 | — | — | US | claimed |
| US-4111703-A | HEAT-SENSITIVE COATING COMPOSITION WITH 4-AROMATIC AND HYDROXY SUBSTITUTED PIPERIDINE DERIVATIVE AND CYCLIC POLYKETO COMPOUND | GRAPHIC CONTROLS CORPORATION (US) | 1978-09-05 | — | — | US | claimed |
| US-4086234-A | Process for the preparation of tertiary amines | G. D. SEARLE & CO. (US) | 1978-04-25 | — | — | US | claimed |
| US-4022791-A | ANALGESICS, TRANQUILIZERS | PFIZER INC. (US) | 1977-05-10 | — | — | US | claimed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (3 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20040072876-A1 | Substituted thiazole derivatives bearing 3-pyridyl groups, process for preparing the same and use thereof | CYP17A1, CYP21A2, HSD17B1 | DRD2 4715/4885MAPKAPK2 3654/4885CCR3 1000/4885 |
| US-10253006-B2 | Assay for the detection of the phenylpiperazine family | METAP2, DCPS, NPEPPS | DRD2 690/4885MAPKAPK2 694/4885CCR3 2326/4885 |
| US-20160229824-A1 | ASSAY FOR THE DETECTION OF THE PHENYLPIPERAZINE FAMILY | METAP2, DCPS, NPEPPS | DRD2 690/4885MAPKAPK2 694/4885CCR3 2326/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.