SCHEMBL1877302

SCHEMBL1877302

Nc1cc([N+](=O)[O-])cc(C(=O)O)c1O

nearest known ligand 0.62

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
ALDH1A1 P00352 4/20 0.62
TDP1 Q9NUW8 2/20 0.62
CYP3A4 P08684 2/20 0.62
ALOX15 P16050 1/20 0.62
GPR35 Q9HC97 1/20 0.61
GAA P10253 1/20 0.49
THRB P10828 1/20 0.49
LMNA P02545 3/20 0.47
AKR1B1 P15121 1/20 0.47
SMN1; SMN2 Q16637 2/20 0.45
MAPT P10636 2/20 0.45
CA1 P00915 1/20 0.45
CA2 P00918 1/20 0.45
MAPK1 P28482 1/20 0.44
HTT P42858 2/20 0.44
MEN1 O00255 1/20 0.44
KMT2A Q03164 1/20 0.44
MMP2 P08253 1/20 0.43
BCL2L1 Q07817 1/20 0.42
MCL1 Q07820 1/20 0.42

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL29972818 1.00 ALDH1A1 (0.62) ALDH1A1TDP1CYP3A4ALOX15GPR35
Water SCHEMBL9065446 0.98 ALDH1A1 (0.60) ALDH1A1TDP1CYP3A4ALOX15GPR35
SCHEMBL5971372 0.87 AKR1B1 (0.52) ALDH1A1TDP1CYP3A4ALOX15GPR35
SCHEMBL11069492 0.84 GPR35 (0.59) ALDH1A1TDP1CYP3A4ALOX15GPR35
SCHEMBL9381233 0.84 ALDH1A1 (0.64) ALDH1A1TDP1CYP3A4ALOX15GPR35
SCHEMBL10883008 0.82 GPR35 (0.77) ALDH1A1TDP1CYP3A4ALOX15GPR35
SCHEMBL856551 0.81 ALDH1A1 (0.58) ALDH1A1TDP1CYP3A4ALOX15GPR35
3,5-Dinitrosalicylic Acid SCHEMBL27736988 0.81 GPR35 (0.59) ALDH1A1TDP1CYP3A4ALOX15GPR35
SCHEMBL13365083 0.81 ALDH1A1 (0.60) ALDH1A1TDP1CYP3A4ALOX15GPR35
SCHEMBL5924264 0.80 GPR35 (0.54) ALDH1A1TDP1CYP3A4ALOX15GPR35

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 380 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-117737172-A Method for exploring influence of Shi Mei on microbial characteristics of tobacco planting soil in tobacco region 广西中烟工业有限责任公司 2024-03-22 CN claimed
CN-113237837-A Preparation method for improving peanut and corn soil under different planting modes of Colqin sand land 辽宁工程技术大学 2021-08-10 CN claimed
CN-110330963-B Redox-responsive color-changing rare earth supermolecule gel fluorescent material and preparation thereof 华中科技大学 2020-06-02 CN claimed
US-20260146256-A1 YEAST STRAINS EXHIBITING PROLONGED PERSISTENCE DURING A PLURALITY OF FERMENTATION CYCLES DANSTAR FERMENT AG (CH) 2026-05-28 US disclosed
CN-119709524-B Mangrove chitin bacillus FCG-7 and application thereof in preparation of N-acetylglucosamine GUANGXI ACADEMY OF SCIENCES (CN) 2026-05-26 CN disclosed
US-20260071246-A1 HIGHLY-ACTIVE RHIZOMA DIOSCOREAE POLYSACCHARIDE AND PREPARATION METHOD THEREOF SERICULTURAL & AGRI FOOD RES INSTITUTE GUANGDONG ACADEMY OF AGRICULTURAL SCIENCES (CN) 2026-03-12 US disclosed
US-20260009011-A1 METHODS AND COMPOSITIONS FOR TREATING CONGENITAL SUCRASE-ISOMALTASE DEFICIENCY ANAGRAM THERAPEUTICS INC (US) 2026-01-08 US disclosed
US-12385052-B2 Yeast strains exhibiting prolonged persistence during a plurality of fermentation cycles DANSTAR FERMENT AG (CH) 2025-08-12 US disclosed
US-20250236878-A1 COMPOSITIONS FOR TREATING CITRUS DISEASE AND PROMOTING YIELD INCREASE IN ROW CROPS SPOGEN BIOTECH INC. 2025-07-24 US disclosed
US-12364719-B2 Bacillus subtilis strains improving animal performance parameters CHR. HANSEN A/S (DK) 2025-07-22 US disclosed
CN-120190205-A Electric strengthening and repairing method for organic contaminated soil 黑龙江大学 2025-06-24 CN disclosed
EP-0456673-A1 PREPARATION FOR DENTAL AND ORAL HYGIENE CONTAINING POLYSACCHARIDE-SPLITTING ENZYMES Henkel Kommanditgesellschaft auf Aktien (DE) 1991-11-21 EP disclosed
EP-0382020-A2 Mouth and teeth care composition containing polysaccharide-lysing enzymes Henkel Kommanditgesellschaft auf Aktien (DE) 1990-08-16 EP disclosed
WO-1990008532-A2 PREPARATION FOR DENTAL AND ORAL HYGIENE CONTAINING POLYSACCHARIDE-SPLITTING ENZYMES HENKEL KOMMANDITGESELLSCHAFT AUF AKTIEN (DE) 1990-08-09 WO disclosed
EP-0368429-A2 Fluor-substituted benzene derivatives SCHERING AKTIENGESELLSCHAFT (DE) 1990-05-16 EP disclosed
EP-0054230-B1 MONOAZO DYESTUFFS AND USE AS IMAGE-FORMING DYESTUFFS IN COLOUR-PHOTOGRAPHIC REGISTRATION MATERIALS Agfa-Gevaert AG (DE) 1985-03-20 EP disclosed
US-4396710-A Photographic recording material with metal complexable, heterocyclic azo dye AFGA-GEVAERT AKTIENGESELLSCHAFT (DE) 1983-08-02 US disclosed
EP-0054230-A2 Monoazo dyestuffs and use as image-forming dyestuffs in colour-photographic registration materials Agfa-Gevaert AG (DE) 1982-06-23 EP disclosed
US-4113880-A ANTIALLERGENS THE UPJOHN COMPANY (US) 1978-09-12 US disclosed
US-4006239-A Benzoic acid amides for mycobacterium infections BAYER AKTIENGESELLSCHAFT (DT) 1977-02-01 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (3 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20260009011-A1 METHODS AND COMPOSITIONS FOR TREATING CONGENITAL SUCRASE-ISOMALTASE DEFICIENCY IDUA, IDE, PRKCSH ALDH1A1 3258/4885TDP1 1274/4885CYP3A4 4381/4885
US-20260146256-A1 YEAST STRAINS EXHIBITING PROLONGED PERSISTENCE DURING A PLURALITY OF FERMENTATION CYCLES SPPL2A, AGL, SORD ALDH1A1 2739/4885TDP1 1912/4885CYP3A4 2995/4885
US-20260071246-A1 HIGHLY-ACTIVE RHIZOMA DIOSCOREAE POLYSACCHARIDE AND PREPARATION METHOD THEREOF LRBA, MRPS17, RPLP1 ALDH1A1 2793/4885TDP1 4205/4885CYP3A4 2958/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.