SCHEMBL18774858

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

	Compound	similarity	top predicted	shared targets
	SCHEMBL18774880	0.86	NPC1 (0.49)	NPC1RAB9AALOX5MAPT
	SCHEMBL11977696	0.80	ALOX5 (0.50)	S1PR1LMNAKDM4ESMN1; SMN2TP53
	SCHEMBL18774886	0.78	NPC1 (0.52)	S1PR1LMNAKDM4ESMN1; SMN2TP53
	SCHEMBL24662854	0.77	NPC1 (0.51)	KDM4ESMN1; SMN2TP53NPC1RAB9A
	SCHEMBL10017246	0.74	CYP2D6 (0.42)	LMNAKDM4ESMN1; SMN2TP53NPC1
	SCHEMBL10893667	0.73	ALDH1A1 (0.50)	LMNAKDM4ESMN1; SMN2ALOX5MAPT
	SCHEMBL17320763	0.72	NPC1 (0.46)	KDM4ESMN1; SMN2NPC1RAB9ADHFR
	SCHEMBL13649228	0.72	CYP1A2 (0.54)	KDM4ENPC1RAB9AHSD17B10ALDH1A1
	SCHEMBL24662631	0.72	NPC1 (0.49)	KDM4ENPC1RAB9AL3MBTL1BTK
	SCHEMBL16303067	0.71	NPC1 (0.49)	KDM4ESMN1; SMN2NPC1RAB9AMAPT

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.