Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ACSS2 | Q9NR19 | 3/20 | 0.36 |
| ▸ | CYSLTR2 | Q9NS75 | 2/20 | 0.33 |
| ▸ | CYSLTR1 | Q9Y271 | 2/20 | 0.33 |
| ▸ | MT-CO1 | P00395 | 2/20 | 0.33 |
| ▸ | MT-CO2 | P00403 | 2/20 | 0.33 |
| ▸ | AR | P10275 | 1/20 | 0.32 |
| ▸ | EDNRA | P25101 | 1/20 | 0.31 |
| ▸ | OPRM1 | P35372 | 1/20 | 0.31 |
| ▸ | HTR2B | P41595 | 1/20 | 0.31 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.31 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.31 |
| ▸ | TNF | P01375 | 1/20 | 0.31 |
| ▸ | NOD2 | Q9HC29 | 1/20 | 0.31 |
| ▸ | NOD1 | Q9Y239 | 1/20 | 0.31 |
| ▸ | ALOX5AP | P20292 | 3/20 | 0.31 |
| ▸ | LMNA | P02545 | 1/20 | 0.31 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.31 |
| ▸ | CYP19A1 | P11511 | 1/20 | 0.30 |
| ▸ | CYP11B1 | P15538 | 1/20 | 0.30 |
| ▸ | CYP11B2 | P19099 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL18791986 | 0.89 | ACSS2 (0.33) | ACSS2MT-CO1MT-CO2AREDNRA | |
| SCHEMBL20111256 | 0.83 | ACSS2 (0.42) | ACSS2CYSLTR2CYSLTR1MT-CO1MT-CO2 | |
| SCHEMBL20111257 | 0.83 | CYP11B2 (0.35) | ACSS2MT-CO1MT-CO2CYP19A1CYP11B1 | |
| SCHEMBL18779248 | 0.83 | CYP11B2 (0.35) | ACSS2MT-CO1MT-CO2CYP19A1CYP11B1 | |
| SCHEMBL18779265 | 0.83 | ACSS2 (0.42) | ACSS2CYSLTR2CYSLTR1MT-CO1MT-CO2 | |
| SCHEMBL18791841 | 0.78 | LMNA (0.34) | ACSS2KCNH2KDM4ETNFNOD2 | |
| SCHEMBL18791842 | 0.77 | ACACB (0.34) | ACSS2KCNH2KDM4ETNFNOD2 | |
| SCHEMBL18779245 | 0.76 | PTGES (0.33) | ACSS2KDM4ETNFNOD2NOD1 | |
| SCHEMBL19276193 | 0.76 | LMNA (0.31) | LMNASMN1; SMN2 | |
| SCHEMBL18779275 | 0.76 | ACACB (0.34) | KCNH2KDM4ETNFNOD2NOD1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-11724990-B2 | Kv7 channel activators compositions and methods of use | BIOHAVEN THERAPEUTICS LTD. (VG) | 2023-08-15 | — | — | US | disclosed |
| US-20170114022-A1 | BENZOIMIDAZOL-1,2-YL AMIDES AS Kv7 CHANNEL ACTIVATORS | CHANNEL BIOSCIENCES, LLC | 2017-04-27 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-11724990-B2 | Kv7 channel activators compositions and methods of use | KCNA7, KCNK17, KCNAB1 | ACSS2 2521/4885CYSLTR2 2068/4885CYSLTR1 2527/4885 |
| US-20170114022-A1 | BENZOIMIDAZOL-1,2-YL AMIDES AS Kv7 CHANNEL ACTIVATORS | KCNA7, KCNJ2, KCNK17 | ACSS2 928/4885CYSLTR2 1191/4885CYSLTR1 1685/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.