Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 6/20 | 0.46 |
| ▸ | CASP1 | P29466 | 5/20 | 0.45 |
| ▸ | TSHR | P16473 | 3/20 | 0.42 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.42 |
| ▸ | RECQL | P46063 | 1/20 | 0.40 |
| ▸ | PDE10A | Q9Y233 | 1/20 | 0.38 |
| ▸ | MAPT | P10636 | 3/20 | 0.37 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.37 |
| ▸ | LMNA | P02545 | 2/20 | 0.37 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.37 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.37 |
| ▸ | ABL1 | P00519 | 1/20 | 0.37 |
| ▸ | BCR | P11274 | 1/20 | 0.37 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.37 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.37 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.37 |
| ▸ | DDX3X | O00571 | 1/20 | 0.35 |
| ▸ | PLA2G7 | Q13093 | 1/20 | 0.34 |
| ▸ | MEN1 | O00255 | 3/20 | 0.34 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL15087203 | 0.84 | MAPT (0.47) | ALDH1A1CASP1TSHRCYP3A4RECQL | |
| SCHEMBL15919625 | 0.79 | GAA (0.50) | ALDH1A1TSHRKDM4ELMNACYP1A2 | |
| SCHEMBL15087198 | 0.76 | RAPGEF4 (0.50) | ALDH1A1TSHRMAPTKDM4ELMNA | |
| SCHEMBL293258 | 0.74 | ALDH1A1 (0.54) | ALDH1A1CASP1TSHRCYP3A4RECQL | |
| SCHEMBL29633200 | 0.74 | ALDH1A1 (0.54) | ALDH1A1CASP1TSHRCYP3A4RECQL | |
| SCHEMBL12065127 | 0.72 | ALDH1A1 (0.52) | ALDH1A1CASP1TSHRCYP3A4RECQL | |
| Hydrochloric Acid SCHEMBL11438180 | 0.72 | ALDH1A1 (0.52) | ALDH1A1CASP1TSHRCYP3A4RECQL | |
| SCHEMBL22778507 | 0.72 | ALDH1A1 (0.52) | ALDH1A1CASP1TSHRCYP3A4RECQL | |
| Hydrochloric Acid SCHEMBL11453440 | 0.72 | ALDH1A1 (0.52) | ALDH1A1CASP1TSHRCYP3A4RECQL | |
| SCHEMBL11289487 | 0.72 | MAPT (0.51) | ALDH1A1CASP1TSHRCYP3A4PDE10A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2020238220-A1 | METHOD FOR PREPARING PAZOPANIB HYDROCHLORIDE | 济南爱思医药科技有限公司 | 2020-12-03 | — | — | WO | claimed |
| US-20170114025-A1 | METHODS FOR INHIBITING NECROPTOSIS | CATALYST THERAPEUTICS PTY LTD (AU) | 2017-04-27 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20170114025-A1 | METHODS FOR INHIBITING NECROPTOSIS | RIPK1, RIPK3, RIPK2 | ALDH1A1 4794/4885CASP1 16/4885TSHR 4307/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.