Niacin

Niacin

SCHEMBL1878451

CCCC[Sn+](CCCC)CCCC.O=C([O-])c1cccnc1

nearest known ligand 0.54

Full drug profile on Sugi Atlas →

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
L3MBTL1 Q9Y468 1/20 0.54
LMNA P02545 4/20 0.51
HDAC3 O15379 1/20 0.51
HDAC1 Q13547 1/20 0.51
HDAC2 Q92769 1/20 0.51
CYP1A2 P05177 1/20 0.49
CYP2C9 P11712 1/20 0.49
TSHR P16473 1/20 0.49
CYP2C19 P33261 1/20 0.49
MAPT P10636 4/20 0.46
NFKB1 P19838 2/20 0.46
NFKB2 Q00653 2/20 0.46
RELA Q04206 2/20 0.46
NPC1 O15118 1/20 0.46
POLB P06746 1/20 0.46
SMN1; SMN2 Q16637 1/20 0.46
ALDH1A1 P00352 4/20 0.45
HTT P42858 1/20 0.45
APP P05067 1/20 0.45
GAA P10253 1/20 0.45

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
Tetrabuthylammonium SCHEMBL5991813 0.82 LMNA (0.55) L3MBTL1LMNAHDAC3HDAC1HDAC2
Isonicotinic Acid SCHEMBL1525686 0.81 HDAC3 (0.46) LMNAHDAC3HDAC1HDAC2CYP1A2
Benzoic Acid SCHEMBL406195 0.81 CA2 (0.55) LMNASMN1; SMN2ALDH1A1
Niacin SCHEMBL27907758 0.80 L3MBTL1 (0.51) L3MBTL1LMNAHDAC3HDAC1HDAC2
Didecyldimethylammonium SCHEMBL5055335 0.79 LMNA (0.54) L3MBTL1LMNAHDAC3HDAC1HDAC2
Terephthalic Acid SCHEMBL1525820 0.79 CA2 (0.44) MAPT
Niacin SCHEMBL25269786 0.79 ALDH1A1 (0.63) LMNAHDAC1CYP1A2MAPTALDH1A1
Niacin SCHEMBL308681 0.79 ALDH1A1 (0.63) LMNAHDAC1CYP1A2MAPTALDH1A1
Niacin SCHEMBL3498987 0.79 ALDH1A1 (0.63) LMNAHDAC1CYP1A2MAPTALDH1A1
Niacin SCHEMBL987479 0.79 ALDH1A1 (0.63) LMNAHDAC1CYP1A2MAPTALDH1A1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 102 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-3034547-B1 A process for the preparation of a block copolymer comprising a first polyolefin block and a second polymer block SABIC GLOBAL TECHNOLOGIES BV (NL) 2019-10-09 EP claimed
EP-3034545-A1 A process for the preparation of a graft copolymer comprising a polyolefin main chain and one or a multiple polymer side chains and the products obtained therefrom SABIC Global Technologies B.V. (NL) 2016-06-22 EP claimed
EP-3034547-A1 A process for the preparation of a block copolymer comprising a first polyolefin block and a second polymer block and the products obtained therefrom SABIC Global Technologies B.V. (NL) 2016-06-22 EP claimed
US-7934888-B2 Marine anti-foulant system and methods for using same VIV SUPPRESSION, INC. (US) 2011-05-03 US claimed
US-20090185867-A1 MARINE ANTI-FOULANT SYSTEM AND METHODS FOR USING SAME ASSET INTEGRITY MANAGEMENT SOLUTIONS, L.L.C., D/B/A AIMS INTERNATIONAL 2009-07-23 US claimed
US-4270953-A STORAGE STABILITY KANSAI PAINT CO., LTD. (JP) 1981-06-02 US claimed
CN-107849816-B Method for treating paperboard and paper media and related treated paperboard and paper media 巴斯夫欧洲公司 2021-07-09 CN disclosed
CN-107922571-B Antifouling composition 巴斯夫聚氨酯特种产品(中国)有限公司 2021-04-30 CN disclosed
EP-3577171-B1 AQUEOUS SYSTEM FOR FORMING A COATING ON A SUBSTRATE BASF SE (DE) 2020-11-18 EP disclosed
US-10829636-B2 Antifouling composition BASF SE (DE) 2020-11-10 US disclosed
EP-3034545-B1 A PROCESS FOR THE PREPARATION OF A GRAFT COPOLYMER COMPRISING A POLYOLEFIN MAIN CHAIN AND ONE OR A MULTIPLE POLYMER SIDE CHAINS AND THE PRODUCTS OBTAINED THEREFROM SABIC GLOBAL TECHNOLOGIES BV (NL) 2020-11-04 EP disclosed
US-10815383-B2 Pigmented primer composition for forming an n-acyl urea coating BASF SE (DE) 2020-10-27 US disclosed
CN-108137951-B Pigmented primer composition for forming N-acylurea coatings 巴斯夫欧洲公司 2020-10-20 CN disclosed
EP-0204456-A1 A hydrolyzable resin composition and an antifouling coating composition containing the same Nippon Paint Co., Ltd. (JP) 1986-12-10 EP disclosed
US-4613373-A ANTIFOULING, ANTIFUNGAL, ANTISEPTIC HOKKO CHEMICAL INDUSTRY CO., LTD. (JP) 1986-09-23 US disclosed
US-4424288-A Carbodiimide-modified polymethylene polyphenylene polyisocyanates for use in the preparation of polyisocyanurate-polyurethane foams BASF WYANDOTTE CORPORATION (US) 1984-01-03 US disclosed
US-4284730-A Liquid carbodiimide- and uretonimine-isocyanurate-containing polyisocyanate compositions and microcellular foams made therefrom BASF WYANDOTTE CORPORATION (US) 1981-08-18 US disclosed
US-4270953-A STORAGE STABILITY KANSAI PAINT CO., LTD. (JP) 1981-06-02 US disclosed
US-4228095-A Process for the preparation of liquid carbodiimide-modified organic polyisocyanates employing organotin catalysts BASF WYANDOTTE CORPORATION (US) 1980-10-14 US disclosed
US-4018708-A TRANSESTERIFICATION CATALYSTS BASF WYANDOTTE CORPORATION (US) 1977-04-19 US disclosed