SCHEMBL1878465

SCHEMBL1878465

Nc1cccc(C(=O)Cc2ccccc2)c1N

nearest known ligand 0.47

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
KDM4E B2RXH2 2/20 0.47
NSD2 O96028 2/20 0.46
MEN1 O00255 1/20 0.46
KMT2A Q03164 1/20 0.46
CES2 O00748 1/20 0.45
CES1 P23141 1/20 0.45
AKR1B1 P15121 1/20 0.45
TP53 P04637 2/20 0.45
L3MBTL1 Q9Y468 2/20 0.45
HIF1A Q16665 2/20 0.45
TDP1 Q9NUW8 2/20 0.45
NPC1 O15118 1/20 0.45
ALDH1A1 P00352 1/20 0.45
GLA P06280 1/20 0.45
CYP3A4 P08684 1/20 0.45
HPGD P15428 1/20 0.45
TSHR P16473 1/20 0.45
MAPK1 P28482 1/20 0.45
RAB9A P51151 1/20 0.45
SMN1; SMN2 Q16637 1/20 0.45

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL4175858 0.87 KDM4E (0.56) KDM4ENSD2MEN1KMT2ACES2
SCHEMBL4451261 0.86 ESR1 (0.51) KDM4EMEN1KMT2ATP53HIF1A
SCHEMBL10954405 0.86 G6PD (0.52) KDM4EMEN1KMT2ACES2CES1
Hydrochloric Acid SCHEMBL9151636 0.85 KDM4E (0.54) KDM4ENSD2MEN1KMT2ACES2
SCHEMBL3278890 0.83 SMN1; SMN2 (0.49) KDM4EMEN1KMT2ACES2CES1
SCHEMBL3279897 0.83 HTT (0.49) MEN1KMT2ACES2CES1AKR1B1
SCHEMBL28041433 0.81 MEN1 (0.43) KDM4EMEN1KMT2ACES2CES1
SCHEMBL7129795 0.80 MEN1 (0.62) MEN1KMT2ACES2CES1AKR1B1
SCHEMBL10582732 0.77 MMP2 (0.44) KDM4ENSD2MEN1KMT2ATP53
SCHEMBL3742604 0.76 NR4A2 (0.47) KDM4EMEN1KMT2AHIF1ATDP1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 9 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-9822205-B2 Deoxybenzoin-derived anti-flammable polymers UNIVERSITY OF MASSACHUSETTS (US) 2017-11-21 US disclosed
US-9340635-B2 Deoxybenzoin-derived anti-flammable polymers UNIVERSITY OF MASSACHUSETTS (US) 2016-05-17 US disclosed
US-20160009854-A1 DEOXYBENZOIN-DERIVED ANTI-FLAMMABLE POLYMERS UNIVERSITY OF MASSACHUSETTS 2016-01-14 US disclosed
US-20160009841-A1 DEOXYBENZOIN-DERIVED ANTI-FLAMMABLE POLYMERS UNIVERSITY OF MASSACHUSETTS 2016-01-14 US disclosed
US-9175131-B2 Deoxybenzoin-derived anti-flammable polymers UNIVERSITY OF MASSACHUSETTS (US) 2015-11-03 US disclosed
US-20130102754-A1 DEOXYBENZOIN-DERIVED ANTI-FLAMMABLE POLYMERS UNIVERSITY OF MASSACHUSETTS (US) 2013-04-25 US disclosed
US-8314202-B2 Deoxybenzoin-derived anti-flammable polymers UNIVERSITY OF MASSACHUSETTS (US) 2012-11-20 US disclosed
US-20110112241-A1 DEOXYBENZOIN-DERIVED ANTI-FLAMMABLE POLYMERS UNIVERSITY OF MASSACHUSETTS 2011-05-12 US disclosed
WO-2009123969-A2 DEOXYBENZOIN-DERIVED ANTI-FLAMMABLE POLYMERS UNIVERSITY OF MASSACHUSETTS (US) 2009-10-08 WO disclosed