Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MTNR1A | P48039 | 3/20 | 0.50 |
| ▸ | MAPT | P10636 | 3/20 | 0.44 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.44 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.44 |
| ▸ | CYP19A1 | P11511 | 2/20 | 0.43 |
| ▸ | FFAR1 | O14842 | 2/20 | 0.42 |
| ▸ | SMN1; SMN2 | Q16637 | 4/20 | 0.40 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.40 |
| ▸ | TSHR | P16473 | 1/20 | 0.40 |
| ▸ | LMNA | P02545 | 1/20 | 0.40 |
| ▸ | NPC1 | O15118 | 2/20 | 0.39 |
| ▸ | RAB9A | P51151 | 1/20 | 0.39 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.39 |
| ▸ | USP2 | O75604 | 1/20 | 0.39 |
| ▸ | MEN1 | O00255 | 1/20 | 0.39 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1874963 | 0.81 | CA2 (0.44) | MTNR1AMAPTMAPK1TDP1ALDH1A1 | |
| SCHEMBL1878665 | 0.81 | MTNR1A (0.51) | MTNR1AMAPTMAPK1TDP1CYP19A1 | |
| SCHEMBL22158332 | 0.78 | MTNR1A (0.55) | MTNR1AMAPTCYP19A1FFAR1SMN1; SMN2 | |
| SCHEMBL7435383 | 0.76 | MTNR1A (0.56) | MTNR1AMAPTTDP1FFAR1SMN1; SMN2 | |
| SCHEMBL7435365 | 0.76 | MTNR1A (0.50) | MTNR1AMAPTMAPK1TDP1CYP19A1 | |
| SCHEMBL6982719 | 0.76 | MTNR1A (0.63) | MTNR1AMAPTFFAR1ALDH1A1MEN1 | |
| SCHEMBL9208736 | 0.76 | MTNR1A (0.60) | MTNR1AMAPTFFAR1ALDH1A1MEN1 | |
| SCHEMBL7199006 | 0.76 | MTNR1A (0.60) | MTNR1AMAPTMAPK1TDP1CYP19A1 | |
| SCHEMBL1870686 | 0.76 | MTNR1A (0.63) | MTNR1AMAPTFFAR1ALDH1A1MEN1 | |
| SCHEMBL29444764 | 0.76 | MTNR1A (0.63) | MTNR1AMAPTFFAR1ALDH1A1MEN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20110105462-A1 | MODULATORS OF DOPAMINE NEUROTRANSMISSION | NSAB, FILIAL AF NEUROSEARCH SWEDEN AB, SVERIGE (DK) | 2011-05-05 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20110105462-A1 | MODULATORS OF DOPAMINE NEUROTRANSMISSION | DBH, SLC18A2, SLC6A3 | MTNR1A 73/4885MAPT 1167/4885MAPK1 2258/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.