⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8189733 | 0.82 | TDP1 (0.34) | — | |
| SCHEMBL5873703 | 0.81 | — | — | |
| SCHEMBL6833631 | 0.79 | TDP1 (0.33) | — | |
| SCHEMBL4891567 | 0.79 | TDP1 (0.33) | — | |
| SCHEMBL7267095 | 0.76 | POLB (0.45) | — | |
| Imidazole SCHEMBL4579994 | 0.73 | — | — | |
| SCHEMBL7327907 | 0.72 | MMP13 (0.36) | — | |
| SCHEMBL9320151 | 0.72 | TPSAB1 (0.43) | — | |
| SCHEMBL29914784 | 0.72 | GAA (0.40) | — | |
| SCHEMBL29683397 | 0.71 | HTR2C (0.34) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3170812-B1 | IMIDAZOLE COMPOUND AND LIPOSOME CONTAINING SAME | FUJIFILM CORP (JP) | 2019-05-29 | — | — | EP | disclosed |
| US-9795566-B2 | Imidazole compound and liposome containing same | FUJIFILM CORPORATION (JP) | 2017-10-24 | — | — | US | disclosed |
| EP-3170812-A1 | IMIDAZOLE COMPOUND AND LIPOSOME CONTAINING SAME | Fujifilm Corporation (JP) | 2017-05-24 | — | — | EP | disclosed |
| US-20170119667-A1 | IMIDAZOLE COMPOUND AND LIPOSOME CONTAINING SAME | FUJIFILM CORPORATION (JP) | 2017-05-04 | — | — | US | disclosed |