Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | FFAR1 | O14842 | 1/20 | 0.43 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.42 |
| ▸ | MAPT | P10636 | 1/20 | 0.42 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.42 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.42 |
| ▸ | MAOB | P27338 | 2/20 | 0.39 |
| ▸ | LIPE | Q05469 | 1/20 | 0.39 |
| ▸ | BRD4 | O60885 | 3/20 | 0.39 |
| ▸ | CREBBP | Q92793 | 1/20 | 0.39 |
| ▸ | MAPK14 | Q16539 | 1/20 | 0.39 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.38 |
| ▸ | APP | P05067 | 1/20 | 0.38 |
| ▸ | MEN1 | O00255 | 2/20 | 0.38 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.38 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.38 |
| ▸ | TTR | P02766 | 1/20 | 0.38 |
| ▸ | BLM | P54132 | 1/20 | 0.38 |
| ▸ | PLA2G1B | P04054 | 1/20 | 0.38 |
| ▸ | POLB | P06746 | 1/20 | 0.38 |
| ▸ | HTT | P42858 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL18788902 | 0.88 | FFAR1 (0.42) | FFAR1L3MBTL1MAPTMAPK1TDP1 | |
| SCHEMBL18788864 | 0.87 | FFAR1 (0.41) | FFAR1L3MBTL1MAPTMAPK1TDP1 | |
| SCHEMBL18788899 | 0.82 | FAAH (0.41) | FFAR1L3MBTL1MAPTMAPK1TDP1 | |
| SCHEMBL18788855 | 0.80 | L3MBTL1 (0.48) | FFAR1L3MBTL1MAPTMAPK1TDP1 | |
| SCHEMBL74678 | 0.78 | MAPT (0.59) | FFAR1L3MBTL1MAPTMAPK1TDP1 | |
| SCHEMBL27656865 | 0.72 | FFAR1 (0.49) | FFAR1L3MBTL1MAPTMAPK1TDP1 | |
| SCHEMBL23258900 | 0.72 | L3MBTL1 (0.52) | FFAR1L3MBTL1MAPTMAPK1TDP1 | |
| SCHEMBL18788854 | 0.71 | APP (0.49) | MAOBAPP | |
| SCHEMBL18788891 | 0.71 | APP (0.49) | MAOBAPPMEN1KMT2A | |
| SCHEMBL2762001 | 0.70 | PRKCA (0.49) | L3MBTL1MAPTMAPK1TDP1MAOB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-10259800-B2 | Method of fluorination using iodonium ylides | THE GENERAL HOSPITAL CORPORATION (US) | 2019-04-16 | — | — | US | disclosed |
| US-20170121300-A1 | METHOD OF FLUORINATION USING IODONIUM YLIDES | THE GENERAL HOSPITAL CORPORATION | 2017-05-04 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20170121300-A1 | METHOD OF FLUORINATION USING IODONIUM YLIDES | FLI1, ABL1, PFAS | FFAR1 1563/4885L3MBTL1 1819/4885MAPT 3346/4885 |
| US-10259800-B2 | Method of fluorination using iodonium ylides | FLI1, ABL1, PFAS | FFAR1 1563/4885L3MBTL1 1819/4885MAPT 3346/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.