Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CHRNB2 | P17787 | 5/20 | 0.53 |
| ▸ | CHRNA4 | P43681 | 5/20 | 0.53 |
| ▸ | BPTF | Q12830 | 1/20 | 0.50 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.49 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.49 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.49 |
| ▸ | HTR1A | P08908 | 2/20 | 0.49 |
| ▸ | CYP2C9 | P11712 | 2/20 | 0.49 |
| ▸ | HTR2A | P28223 | 2/20 | 0.49 |
| ▸ | HTR2C | P28335 | 2/20 | 0.49 |
| ▸ | CYP2C19 | P33261 | 2/20 | 0.49 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.49 |
| ▸ | MEN1 | O00255 | 1/20 | 0.49 |
| ▸ | HPGD | P15428 | 1/20 | 0.49 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.49 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.49 |
| ▸ | HTR3E | A5X5Y0 | 4/20 | 0.47 |
| ▸ | HTR3B | O95264 | 4/20 | 0.47 |
| ▸ | HTR3A | P46098 | 4/20 | 0.47 |
| ▸ | HTR3D | Q70Z44 | 4/20 | 0.47 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8722753 | 0.76 | TRPV1 (0.34) | CHRNB2CHRNA4MEN1KMT2AHRH4 | |
| SCHEMBL31061384 | 0.75 | ADRB1 (0.59) | BPTFALDH1A1CYP1A2CYP3A4HTR1A | |
| SCHEMBL4426193 | 0.75 | ADRB1 (0.59) | BPTFALDH1A1CYP1A2CYP3A4HTR1A | |
| SCHEMBL14982162 | 0.75 | ADRB1 (0.51) | CHRNB2CHRNA4HTR1AHTR2AHTR2C | |
| SCHEMBL1025795 | 0.73 | HTR3E (0.59) | CHRNB2CHRNA4BPTFALDH1A1CYP1A2 | |
| Hydrochloric Acid SCHEMBL31536994 | 0.71 | HTR3E (0.57) | CHRNB2CHRNA4BPTFALDH1A1CYP1A2 | |
| SCHEMBL21582695 | 0.71 | CHRNB2 (0.57) | CHRNB2CHRNA4BPTFALDH1A1CYP1A2 | |
| SCHEMBL1026310 | 0.71 | ADRB1 (0.59) | BPTFALDH1A1CYP1A2CYP3A4HTR1A | |
| SCHEMBL29937735 | 0.71 | ADRB1 (0.59) | BPTFALDH1A1CYP1A2CYP3A4HTR1A | |
| SCHEMBL8339191 | 0.70 | BPTF (0.53) | CHRNB2CHRNA4BPTFALDH1A1CYP1A2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2025054132-A1 | ANTIBACTERIAL COMPOUNDS | ARREPATH, INC. (US) | 2025-03-13 | — | — | WO | disclosed |
| EP-3381904-B1 | NOVEL NITROGEN-CONTAINING AROMATIC HETEROCYCLIC COMPOUND | MITSUBISHI TANABE PHARMA CORP (JP) | 2021-07-28 | — | — | EP | disclosed |
| US-10717731-B2 | Nitrogen-containing aromatic heterocyclic compound | MITSUBISHI TANABE PHARMA CORPORATION (JP) | 2020-07-21 | — | — | US | disclosed |
| WO-2017069226-A1 | NOVEL NITROGEN-CONTAINING AROMATIC HETEROCYCLIC COMPOUND | 田辺三菱製薬株式会社 | 2017-04-27 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-10717731-B2 | Nitrogen-containing aromatic heterocyclic compound | REN, NR3C2, NR5A1 | CHRNB2 3416/4885CHRNA4 3918/4885BPTF 1759/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.